cancer susceptibility

  • TP53, a gene for colorectal cancer predisposition in the absence of Li-Fraumeni-associated phenotypes
    Mariona Terradas, Pilar Mur, Sami Belhadj, Emma R Woodward, George J Burghel, Pau M Munoz-Torres, Isabel Quintana, Matilde Navarro, Joan Brunet, Conxi Lazaro, Marta Pineda, Victor Moreno, Gabriel Capella, D Gareth R Evans, Laura Valle
  • Genetic architectures of proximal and distal colorectal cancer are partly distinct
    Jeroen R Huyghe, Tabitha A Harrison, Stephanie A Bien, Heather Hampel, Jane C Figueiredo, Stephanie L Schmit, David V Conti, Sai Chen, Conghui Qu, Yi Lin, Richard Barfield, John A Baron, Amanda J Cross, Brenda Diergaarde, David Duggan, Sophia Harlid, Liher Imaz, Hyun Min Kang, David M Levine, Vittorio Perduca, Aurora Perez-Cornago, Lori C Sakoda, Fredrick R Schumacher, Martha L Slattery, Amanda E Toland, Fränzel J B van Duijnhoven, Bethany Van Guelpen, Antonio Agudo, Demetrius Albanes, M Henar Alonso, Kristin Anderson, Coral Arnau-Collell, Volker Arndt, Barbara L Banbury, Michael C Bassik, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Heiner Boeing, Marie-Christine Boutron-Ruault, Hermann Brenner, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Andrea Burnett-Hartman, Bette J Caan, Peter T Campbell, Prudence R Carr, Antoni Castells, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Keith R Curtis, Albert de la Chapelle, Douglas F Easton, Dallas R English, Edith J M Feskens, Manish Gala, Steven J Gallinger, W James Gauderman, Graham G Giles, Phyllis J Goodman, William M Grady, John S Grove, Andrea Gsur, Marc J Gunter, Robert W Haile, Jochen Hampe, Michael Hoffmeister, John L Hopper, Wan-Ling Hsu, Wen-Yi Huang, Thomas J Hudson, Mazda Jenab, Mark A Jenkins, Amit D Joshi, Temitope O Keku, Charles Kooperberg, Tilman Kühn, Sébastien Küry, Loic Le Marchand, Flavio Lejbkowicz, Christopher I Li, Li Li, Wolfgang Lieb, Annika Lindblom, Noralane M Lindor, Satu Männistö, Sanford D Markowitz, Roger L Milne, Lorena Moreno, Neil Murphy, Rami Nassir, Kenneth Offit, Shuji Ogino, Salvatore Panico, Patrick S Parfrey, Rachel Pearlman, Paul D P Pharoah, Amanda I Phipps, Elizabeth A Platz, John D Potter, Ross L Prentice, Lihong Qi, Leon Raskin, Gad Rennert, Hedy S Rennert, Elio Riboli, Clemens Schafmayer, Robert E Schoen, Daniela Seminara, Mingyang Song, Yu-Ru Su, Catherine M Tangen, Stephen N Thibodeau, Duncan C Thomas, Antonia Trichopoulou, Cornelia M Ulrich, Kala Visvanathan, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Korbinian Weigl, Stephanie J Weinstein, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Goncalo R Abecasis, Deborah A Nickerson, Peter C Scacheri, Anshul Kundaje, Graham Casey, Stephen B Gruber, Li Hsu, Victor Moreno, Richard B Hayes, Polly A Newcomb, Ulrike Peters
  • Evidence suggests that germline RNF43 mutations are a rare cause of serrated polyposis
    Isabel Quintana, Raquel Mejías-Luque, Mariona Terradas, Matilde Navarro, Virginia Piñol, Pilar Mur, Sami Belhadj, Elia Grau, Esther Darder, Ares Solanes, Joan Brunet, Gabriel Capellá, Markus Gerhard, Laura Valle
  • High impact of methylation accumulation on metachronous gastric cancer: 5-year follow-up of a multicentre prospective cohort study
    Masahiro Maeda, Takeshi Nakajima, Ichiro Oda, Taichi Shimazu, Nobutake Yamamichi, Takao Maekita, Kiyoshi Asada, Chizu Yokoi, Takayuki Ando, Takeichi Yoshida, Sohachi Nanjo, Mitsuhiro Fujishiro, Takuji Gotoda, Masao Ichinose, Toshikazu Ushijima
  • Genetic variant PLCE1 rs2274223 and gastric cancer: more to be explored?
    Yazhou He, Chengdi Wang, Ziqiang Wang, Zongguang Zhou
  • Functional annotation of high-quality SNP biomarkers of gastric cancer susceptibility: the Yin Yang of PSCA rs2294008
    Hyuna Sung, Howard H Yang, Nan Hu, Hua Su, Philip R Taylor, Paula L Hyland
  • Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype
    Nuria Seguí, Matilde Navarro, Marta Pineda, Nicole Köger, Fernando Bellido, Sara González, Olga Campos, Silvia Iglesias, Rafael Valdés-Mas, Adriana López-Doriga, Marta Gut, Ignacio Blanco, Conxi Lázaro, Gabriel Capellá, Xose S Puente, Guido Plotz, Laura Valle
  • A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk
    Meian He, Chen Wu, Jianfeng Xu, Huan Guo, Handong Yang, Xiaomin Zhang, Jielin Sun, Dianke Yu, Li Zhou, Tao Peng, Yunfeng He, Yong Gao, Jing Yuan, Qifei Deng, Xiayun Dai, Aihua Tan, Yingying Feng, Haiying Zhang, Xinwen Min, Xiaobo Yang, Jiang Zhu, Kan Zhai, Jiang Chang, Xue Qin, Wen Tan, Yanling Hu, Mingjian Lang, Sha Tao, Yuanfeng Li, Yi Li, Junjie Feng, Dongfeng Li, Seong-Tae Kim, Shijun Zhang, Hongxing Zhang, S Lilly Zheng, Lixuan Gui, Youjie Wang, Sheng Wei, Feng Wang, Weimin Fang, Yuan Liang, Yun Zhai, Weihong Chen, Xiaoping Miao, Gangqiao Zhou, Frank B Hu, Dongxin Lin, Zengnan Mo, Tangchun Wu
  • Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals
    Malcolm G Dunlop, Albert Tenesa, Susan M Farrington, Stephane Ballereau, David H Brewster, Thibaud Koessler, Paul Pharoah, Clemens Schafmayer, Jochen Hampe, Henry Völzke, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Susanna von Holst, Simone Picelli, Annika Lindblom, Mark A Jenkins, John L Hopper, Graham Casey, David Duggan, Polly A Newcomb, Anna Abulí, Xavier Bessa, Clara Ruiz-Ponte, Sergi Castellví-Bel, Iina Niittymäki, Sari Tuupanen, Auli Karhu, Lauri Aaltonen, Brent Zanke, Tom Hudson, Steven Gallinger, Ella Barclay, Lynn Martin, Maggie Gorman, Luis Carvajal-Carmona, Axel Walther, David Kerr, Steven Lubbe, Peter Broderick, Ian Chandler, Alan Pittman, Steven Penegar, Harry Campbell, Ian Tomlinson, Richard S Houlston
  • Comparison of the clinical prediction model PREMM1,2,6 and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer
    Fay Kastrinos, Ewout W Steyerberg, Judith Balmaña, Rowena Mercado, Steven Gallinger, Robert Haile, Graham Casey, John L Hopper, Loic LeMarchand, Noralane M Lindor, Polly A Newcomb, Stephen N Thibodeau, Sapna Syngal, the Colon Cancer Family Registry