gastrointestinal immune response

TiO₂ nanoparticles abrogate the protective effect of the Crohn’s disease-associated variation within the PTPN22 gene locus
Marlene Schwarzfischer, Anna Niechcial, Kristina Handler, Yasser Morsy, Marcin Wawrzyniak, Andrea S Laimbacher, Kirstin Atrott, Roberto Manzini, Katharina Baebler, Larissa Hering, Egle Katkeviciutė, Janine Häfliger, Silvia Lang, Maja E Keller, Jérôme Woodtli, Lisa Eisenbeiss, Thomas Kraemer, Elisabeth M Schraner, Mahesa Wiesendanger, Sebastian Zeissig, Gerhard Rogler, Andreas E Moor, Michael Scharl, Marianne R Spalinger

Gut Oct 2022, gutjnl-2021-325911; DOI: 10.1136/gutjnl-2021-325911
CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival
Camille Danne, Chloé Michaudel, Jurate Skerniskyte, Julien Planchais, Aurélie Magniez, Allison Agus, Marie-Laure Michel, Bruno Lamas, Gregory Da Costa, Madeleine Spatz, Cyriane Oeuvray, Chloé Galbert, Maxime Poirier, Yazhou Wang, Alexia Lapière, Nathalie Rolhion, Tatiana Ledent, Cédric Pionneau, Solenne Chardonnet, Floriant Bellvert, Edern Cahoreau, Amandine Rocher, Rafael Rose Arguello, Carole Peyssonnaux, Sabine Louis, Mathias L Richard, Philippe Langella, Jamel El-Benna, Benoit Marteyn, Harry Sokol

Gut Sep 2022, gutjnl-2022-326917; DOI: 10.1136/gutjnl-2022-326917
Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD
Bella Ungar, Miri Yavzori, Ella Fudim, Orit Picard, Uri Kopylov, Rami Eliakim, Dror Shouval, Yishai Levin, Alon Savidor, Shani Ben-Moshe, Rita Manco, Stav Dan, Adi Egozi, Keren Bahar Halpern, Chen Mayer, Iris Barshack, Shomron Ben-Horin, Shalev Itzkovitz

Gut Oct 2022, 71 (10) 1988-1997; DOI: 10.1136/gutjnl-2021-325516
NTPDase8 protects mice from intestinal inflammation by limiting P2Y₆ receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD
Mabrouka Salem, Joanna Lecka, Julie Pelletier, Danielle Gomes Marconato, Aline Dumas, Luc Vallières, Gaetan Brochu, Bernard Robaye, Christian Jobin, Jean Sévigny

Gut Jan 2022, 71 (1) 43-54; DOI: 10.1136/gutjnl-2020-320937
Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium
Ozge Kayisoglu, Franziska Weiss, Carolin Niklas, Isabella Pierotti, Malvika Pompaiah, Nina Wallaschek, Christoph-Thomas Germer, Armin Wiegering, Sina Bartfeld

Gut Apr 2021, 70 (4) 687-697; DOI: 10.1136/gutjnl-2019-319919
Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens
Allison Cabinian, Daniel Sinsimer, May Tang, Youngsoon Jang, Bongkum Choi, Yasmina Laouar, Amale Laouar

Gut May 2018, 67 (5) 847-859; DOI: 10.1136/gutjnl-2016-313214
Presence of commensal house dust mite allergen in human gastrointestinal tract: a potential contributor to intestinal barrier dysfunction
Meri K Tulic, Mylene Vivinus-Nébot, Akila Rekima, Samara Rabelo Medeiros, Chrystelle Bonnart, Haining Shi, Allan Walker, Raffaella Dainese, Julien Boyer, Nathalie Vergnolle, Thierry Piche, Valérie Verhasselt

Gut May 2016, 65 (5) 757-766; DOI: 10.1136/gutjnl-2015-310523
Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation
Toshihiro Matsukawa, Kumi Izawa, Masamichi Isobe, Mariko Takahashi, Akie Maehara, Yoshinori Yamanishi, Ayako Kaitani, Ko Okumura, Takanori Teshima, Toshio Kitamura, Jiro Kitaura

Gut May 2016, 65 (5) 777-787; DOI: 10.1136/gutjnl-2014-308900
Compartment-specific immunity in the human gut: properties and functions of dendritic cells in the colon versus the ileum
Elizabeth R Mann, David Bernardo, Nicholas R English, Jon Landy, Hafid O Al-Hassi, Simon TC Peake, Ripple Man, Timothy R Elliott, Henning Spranger, Gui Han Lee, Alyssa Parian, Steven R Brant, Mark Lazarev, Ailsa L Hart, Xuhang Li, Stella C Knight

Gut Feb 2016, 65 (2) 256-270; DOI: 10.1136/gutjnl-2014-307916
Changing the narrative on antibiotics
Fergus Shanahan

Gut Nov 2015, 64 (11) 1674-1675; DOI: 10.1136/gutjnl-2014-309072

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