gene expression

  • Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study
    Annefleur Koopen, Julia Witjes, Koen Wortelboer, Soumia Majait, Andrei Prodan, Evgeni Levin, Hilde Herrema, Maaike Winkelmeijer, Steven Aalvink, Jacques J G H M Bergman, Stephan Havik, Bolette Hartmann, Han Levels, Per-Olof Bergh, Jamie van Son, Manon Balvers, Diogo Mendes Bastos, Erik Stroes, Albert K Groen, Marcus Henricsson, Ellis Marleen Kemper, Jens Holst, Christopher M Strauch, Stanley L Hazen, Fredrik Bäckhed, Willem M De Vos, Max Nieuwdorp, Elena Rampanelli
  • Interferon regulatory factor 1 (IRF1) controls the metabolic programmes of low-grade pancreatic cancer cells
    Gabriele Alfarano, Matteo Audano, Pierluigi Di Chiaro, Chiara Balestrieri, Marta Milan, Sara Polletti, Paola Spaggiari, Alessandro Zerbi, Giuseppe Riccardo Diaferia, Nico Mitro, Gioacchino Natoli
  • Defining the key intrahepatic gene networks in HCV infection driven by sex
    Emanuele Marchi, Narayan Ramamurthy, M Azim Ansari, Caroline E Harrer, STOP-HCV, Eleanor Barnes, Paul Klenerman
  • Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications
    Miguel A Martin-Serrano, Benjamin Kepecs, Miguel Torres-Martin, Emily R Bramel, Philipp K Haber, Elliot Merritt, Alexander Rialdi, Nesteene Joy Param, Miho Maeda, Katherine E Lindblad, James K Carter, Marina Barcena-Varela, Vincenzo Mazzaferro, Myron Schwartz, Silvia Affo, Robert F Schwabe, Augusto Villanueva, Ernesto Guccione, Scott L Friedman, Amaia Lujambio, Anna Tocheva, Josep M Llovet, Swan N Thung, Alexander M Tsankov, Daniela Sia
  • Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target
    Sarra Smati, Arnaud Polizzi, Anne Fougerat, Sandrine Ellero-Simatos, Yuna Blum, Yannick Lippi, Marion Régnier, Alexia Laroyenne, Marine Huillet, Muhammad Arif, Cheng Zhang, Frederic Lasserre, Alain Marrot, Talal Al Saati, JingHong Wan, Caroline Sommer, Claire Naylies, Aurelie Batut, Celine Lukowicz, Tiffany Fougeray, Blandine Tramunt, Patricia Dubot, Lorraine Smith, Justine Bertrand-Michel, Nathalie Hennuyer, Jean-Philippe Pradere, Bart Staels, Remy Burcelin, Françoise Lenfant, Jean-François Arnal, Thierry Levade, Laurence Gamet-Payrastre, Sandrine Lagarrigue, Nicolas Loiseau, Sophie Lotersztajn, Catherine Postic, Walter Wahli, Christophe Bureau, Maeva Guillaume, Adil Mardinoglu, Alexandra Montagner, Pierre Gourdy, Hervé Guillou
  • Clinical, histological and molecular profiling of different stages of alcohol-related liver disease
    Meritxell Ventura-Cots, Josepmaria Argemi, Patricia D Jones, Carolin Lackner, Mohamed El Hag, Juan G Abraldes, Edilmar Alvarado, Ana Clemente, Samhita Ravi, Antonio Alves, Mohamed Alboraie, Jose Altamirano, Sergio Barace, Francisco Bosques, Robert Brown, Juan Caballeria, Joaquin Cabezas, Sofia Carvalhana, Helena Cortez-Pinto, Adilia Costa, Delphine Degré, Carlos Fernandez-Carrillo, Nathalie Ganne-Carrie, Guadalupe Garcia-Tsao, Joan Genesca, John Koskinas, Nicolas Lanthier, Alexandre Louvet, Juan José Lozano, Michael R Lucey, Steven Masson, Philippe Mathurin, Nahum Mendez-Sanchez, Rosa Miquel, Christophe Moreno, Taofic Mounajjed, Gemma Odena, Won Kim, Pau Sancho-Bru, R Warren Sands, Justyna Szafranska, Laurine Verset, Bern Schnabl, Christine Sempoux, Vijay Shah, Debbie Lindsay Shawcross, Rudolf E Stauber, Beate K Straub, Elizabeth Verna, Dina Tiniakos, Eric Trépo, Victor Vargas, Càndid Villanueva, John T Woosley, Marianne Ziol, Sebastian Mueller, Peter Stärkel, Ramon Bataller
  • Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma—rationale for targeting ARID1A deficiency
    Xiaochuan Dong, Shumei Song, Yuan Li, Yibo Fan, Lulu Wang, Ruiping Wang, Longfei Huo, Ailing Scott, Yan Xu, Melissa Pool Pizzi, Lang Ma, Ying Wang, Jiangkang Jin, Wei Zhao, Xiaodan Yao, Randy L Johnson, Linghua Wang, Zhenning Wang, Guang Peng, Jaffer A Ajani
  • Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma
    Shumei Song, Qiongrong Chen, Yuan Li, Guang Lei, Ailing Scott, Longfei Huo, Cordelia Y Li, Jeannelyn Santiano Estrella, Arlene Correa, Melissa Pool Pizzi, Lang Ma, Jiankang Jin, Bin Liu, Ying Wang, Lianchun Xiao, Wayne L Hofstetter, Jeffrey H Lee, Brian Weston, Manoop Bhutani, Namita Shanbhag, Randy L Johnson, Boyi Gan, Shaozhong Wei, Jaffer A Ajani
  • RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer
    Lei Sun, Arabella Wan, Zhuolong Zhou, Dongshi Chen, Heng Liang, Chuwei Liu, Shijia Yan, Yi Niu, Ziyou Lin, Siyue Zhan, Shanfeng Wang, Xianzhang Bu, Weiling He, Xiongbin Lu, Anlong Xu, Guohui Wan
  • Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer
    Johann von Felden, Teresa Garcia-Lezana, Navneet Dogra, Edgar Gonzalez-Kozlova, Mehmet Eren Ahsen, Amanda Craig, Stacey Gifford, Benjamin Wunsch, Joshua T Smith, Sungcheol Kim, Jennifer E L Diaz, Xintong Chen, Ismail Labgaa, Philipp Haber, Reena Olsen, Dan Han, Paula Restrepo, Delia D'Avola, Gabriela Hernandez-Meza, Kimaada Allette, Robert Sebra, Behnam Saberi, Parissa Tabrizian, Amon Asgharpour, Douglas Dieterich, Josep M. Llovet, Carlos Cordon-Cardo, Ash Tewari, Myron Schwartz, Gustavo Stolovitzky, Bojan Losic, Augusto Villanueva

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