gene expression

  • Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer
    Johann von Felden, Teresa Garcia-Lezana, Navneet Dogra, Edgar Gonzalez-Kozlova, Mehmet Eren Ahsen, Amanda Craig, Stacey Gifford, Benjamin Wunsch, Joshua T Smith, Sungcheol Kim, Jennifer E L Diaz, Xintong Chen, Ismail Labgaa, Philipp Haber, Reena Olsen, Dan Han, Paula Restrepo, Delia D'Avola, Gabriela Hernandez-Meza, Kimaada Allette, Robert Sebra, Behnam Saberi, Parissa Tabrizian, Amon Asgharpour, Douglas Dieterich, Josep M. Llovet, Carlos Cordon-Cardo, Ash Tewari, Myron Schwartz, Gustavo Stolovitzky, Bojan Losic, Augusto Villanueva
  • Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target
    Sarra Smati, Arnaud Polizzi, Anne Fougerat, Sandrine Ellero-Simatos, Yuna Blum, Yannick Lippi, Marion Régnier, Alexia Laroyenne, Marine Huillet, Muhammad Arif, Cheng Zhang, Frederic Lasserre, Alain Marrot, Talal Al Saati, JingHong Wan, Caroline Sommer, Claire Naylies, Aurelie Batut, Celine Lukowicz, Tiffany Fougeray, Blandine Tramunt, Patricia Dubot, Lorraine Smith, Justine Bertrand-Michel, Nathalie Hennuyer, Jean-Philippe Pradere, Bart Staels, Remy Burcelin, Françoise Lenfant, Jean-François Arnal, Thierry Levade, Laurence Gamet-Payrastre, Sandrine Lagarrigue, Nicolas Loiseau, Sophie Lotersztajn, Catherine Postic, Walter Wahli, Christophe Bureau, Maeva Guillaume, Adil Mardinoglu, Alexandra Montagner, Pierre Gourdy, Hervé Guillou
  • Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma—rationale for targeting ARID1A deficiency
    Xiaochuan Dong, Shumei Song, Yuan Li, Yibo Fan, Lulu Wang, Ruiping Wang, Longfei Huo, Ailing Scott, Yan Xu, Melissa Pool Pizzi, Lang Ma, Ying Wang, Jiangkang Jin, Wei Zhao, Xiaodan Yao, Randy L Johnson, Linghua Wang, Zhenning Wang, Guang Peng, Jaffer A Ajani
  • Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4
    Soledad A Camolotto, Veronika K Belova, Luke Torre-Healy, Jeffery M Vahrenkamp, Kristofer C Berrett, Hannah Conway, Jill Shea, Chris Stubben, Richard Moffitt, Jason Gertz, Eric L Snyder
  • Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa
    Laura Reyes-Uribe, Wenhui Wu, Ozkan Gelincik, Prashant V Bommi, Alejandro Francisco-Cruz, Luisa M Solis, Patrick M Lynch, Ramona Lim, Elena M Stoffel, Priyanka Kanth, N Jewel Samadder, Maureen E Mork, Melissa W Taggart, Ginger L Milne, Lawrence J Marnett, Lana Vornik, Diane D Liu, Maria Revuelta, Kyle Chang, Y Nancy You, Levy Kopelovich, Ignacio I Wistuba, J Jack Lee, Shizuko Sei, Robert H Shoemaker, Eva Szabo, Ellen Richmond, Asad Umar, Marjorie Perloff, Powel H Brown, Steven M Lipkin, Eduardo Vilar
  • Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma
    Shumei Song, Qiongrong Chen, Yuan Li, Guang Lei, Ailing Scott, Longfei Huo, Cordelia Y Li, Jeannelyn Santiano Estrella, Arlene Correa, Melissa Pool Pizzi, Lang Ma, Jiankang Jin, Bin Liu, Ying Wang, Lianchun Xiao, Wayne L Hofstetter, Jeffrey H Lee, Brian Weston, Manoop Bhutani, Namita Shanbhag, Randy L Johnson, Boyi Gan, Shaozhong Wei, Jaffer A Ajani
  • Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma
    Frank Jühling, Nourdine Hamdane, Emilie Crouchet, Shen Li, Houssein El Saghire, Atish Mukherji, Naoto Fujiwara, Marine A Oudot, Christine Thumann, Antonio Saviano, Armando Andres Roca Suarez, Kaku Goto, Ricard Masia, Mozhdeh Sojoodi, Gunisha Arora, Hiroshi Aikata, Atsushi Ono, Parissa Tabrizian, Myron Schwartz, Stephen J Polyak, Irwin Davidson, Christian Schmidl, Christoph Bock, Catherine Schuster, Kazuaki Chayama, Patrick Pessaux, Kenneth K Tanabe, Yujin Hoshida, Mirjam B Zeisel, François HT Duong, Bryan C Fuchs, Thomas F Baumert
  • RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer
    Lei Sun, Arabella Wan, Zhuolong Zhou, Dongshi Chen, Heng Liang, Chuwei Liu, Shijia Yan, Yi Niu, Ziyou Lin, Siyue Zhan, Shanfeng Wang, Xianzhang Bu, Weiling He, Xiongbin Lu, Anlong Xu, Guohui Wan
  • Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles
    Helen H N Yan, Hoi Cheong Siu, Siu Lun Ho, Sarah S K Yue, Yang Gao, Wai Yin Tsui, Dessy Chan, April S Chan, Jason W H Wong, Alice H Y Man, Bernard C H Lee, Annie S Y Chan, Anthony K W Chan, Ho Sang Hui, Arthur K L Cheung, Wai Lun Law, Oswens S H Lo, Siu Tsan Yuen, Hans Clevers, Suet Yi Leung
  • Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response
    Ruiping Wang, Shumei Song, Kazuto Harada, Fatemeh Ghazanfari Amlashi, Brian Badgwell, Melissa Pool Pizzi, Yan Xu, Wei Zhao, Xiaochuan Dong, Jiangkang Jin, Ying Wang, Ailing Scott, Lang Ma, Longfei Huo, Diego Vicente, Mariela Blum Murphy, Namita Shanbhag, Ghia Tatlonghari, Irene Thomas, Jane Rogers, Makoto Kobayashi, Jody Vykoukal, Jeannelyn Santiano Estrella, Sinchita Roy-Chowdhuri, Guangchun Han, Shaojun Zhang, Xizeng Mao, Xingzhi Song, Jianhua Zhang, Jian Gu, Randy L Johnson, George Adrian Calin, Guang Peng, Ju-Seog Lee, Samir M Hanash, Andrew Futreal, Zhenning Wang, Linghua Wang, Jaffer A Ajani

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