IBD basic research

Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
Isabelle Cleynen, Emilie Vazeille, Marta Artieda, Hein W Verspaget, Magdalena Szczypiorska, Marie-Agnès Bringer, Peter L Lakatos, Frank Seibold, Kirstie Parnell, Rinse K Weersma, Jestinah M Mahachie John, Rebecca Morgan-Walsh, Dominiek Staelens, Ingrid Arijs, Gert De Hertogh, Stefan Müller, Atilla Tordai, Daniel W Hommes, Tariq Ahmad, Cisca Wijmenga, Sylvia Pender, Paul Rutgeerts, Kristel Van Steen, Daniel Lottaz, Severine Vermeire, Arlette Darfeuille-Michaud

Gut Aug 2014, 63 (8) 1265-1274; DOI: 10.1136/gutjnl-2012-303205
An intestinal arsonist: pathobiont ignites IBD and flees the scene
Stefan Jellbauer, Manuela Raffatellu

Gut Jul 2014, 63 (7) 1034-1035; DOI: 10.1136/gutjnl-2013-305589
Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease
J Jasper Deuring, Gwenny M Fuhler, Sergey R Konstantinov, Maikel P Peppelenbosch, Ernst J Kuipers, Colin de Haar, C Janneke van der Woude

Gut Jul 2014, 63 (7) 1081-1091; DOI: 10.1136/gutjnl-2012-303527
Anti-TNF-α-induced psoriasiform lesions in IBD: an abnormal immune activation or a ‘patchy cutaneous’ immune suppression?
Franco Scaldaferri, Valentina Petito, Alfredo Papa, Monica Cesarini, Vincenzo Arena, Loris Riccardo Lopetuso, Maddalena Corbi, Francesca Perino, Giacomo Caldarola, Angelo Carbone, Enrico Corazziari, Alessandro Sgambato, Antonio Gasbarrini, Clara De Simone

Gut Apr 2014, 63 (4) 699-701; DOI: 10.1136/gutjnl-2013-305478
Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer
Jarom Heijmans, Mattheus C B Wielenga, Sanne Liesbeth Rosekrans, Jooske F van Lidth de Jeude, Joris Roelofs, Patrick Groothuis, Antwan Ederveen, Eveline S M de Jonge-Muller, Izak Biemond, James C H Hardwick, Geert D'Haens, Daniel W Hommes, Vanesa Muncan, Gijs R van den Brink

Gut Feb 2014, 63 (2) 310-316; DOI: 10.1136/gutjnl-2012-304216
Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation
Margarita Martinez-Medina, Jérémy Denizot, Nicolas Dreux, Frédéric Robin, Elisabeth Billard, Richard Bonnet, Arlette Darfeuille-Michaud, Nicolas Barnich

Gut Jan 2014, 63 (1) 116-124; DOI: 10.1136/gutjnl-2012-304119
Mucosal CXCR4⁺ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14 macrophage activation
Michihide Uo, Tadakazu Hisamatsu, Jun Miyoshi, Daiki Kaito, Kazuaki Yoneno, Mina T Kitazume, Maiko Mori, Akira Sugita, Kazutaka Koganei, Katsuyoshi Matsuoka, Takanori Kanai, Toshifumi Hibi

Gut Dec 2013, 62 (12) 1734-1744; DOI: 10.1136/gutjnl-2012-303063
MTG16 contributes to colonic epithelial integrity in experimental colitis
Christopher S Williams, Amber M Bradley, Rupesh Chaturvedi, Kshipra Singh, Maria B Piazuelo, Xi Chen, Elizabeth M McDonough, David A Schwartz, Caroline T Brown, Margaret M Allaman, Lori A Coburn, Sara N Horst, Dawn B Beaulieu, Yash A Choksi, Mary Kay Washington, Amanda D Williams, Melissa A Fisher, Sandra S Zinkel, Richard M Peek, Keith T Wilson, Scott W Hiebert

Gut Oct 2013, 62 (10) 1446-1455; DOI: 10.1136/gutjnl-2011-301439
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis
Paul J Rutgeerts, Richard N Fedorak, Daan W Hommes, Andreas Sturm, Daniel C Baumgart, Brian Bressler, Stefan Schreiber, John C Mansfield, Marna Williams, Meina Tang, Jennifer Visich, Xiaohui Wei, Mary Keir, Diana Luca, Dimitri Danilenko, Jackson Egen, Sharon O'Byrne

Gut Aug 2013, 62 (8) 1122-1130; DOI: 10.1136/gutjnl-2011-301769
Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4 memory T cells
Yasuhiro Nemoto, Takanori Kanai, Masahiro Takahara, Shigeru Oshima, Tetsuya Nakamura, Ryuichi Okamoto, Kiichiro Tsuchiya, Mamoru Watanabe

Gut Aug 2013, 62 (8) 1142-1152; DOI: 10.1136/gutjnl-2012-302029

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