integrins

Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances
Sebastian Zundler, Emily Becker, Lisa Lou Schulze, Markus F Neurath

Gut Sep 2019, 68 (9) 1688-1700; DOI: 10.1136/gutjnl-2018-317977
β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the α_Vβ6 integrin receptor
Patrick Weil, Rhea van den Bruck, Thomas Ziegenhals, Stefan Juranek, Daniel Goedde, Valerie Orth, Stefan Wirth, Andreas C Jenke, Jan Postberg

Gut Jun 2019, gutjnl-2019-319015; DOI: 10.1136/gutjnl-2019-319015
Mechanism of action of vedolizumab: do we really understand it?
Gerhard Rogler

Gut Jan 2019, 68 (1) 4-5; DOI: 10.1136/gutjnl-2018-316777
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Sebastian Zeissig, Elisa Rosati, C Marie Dowds, Konrad Aden, Johannes Bethge, Berenice Schulte, Wei Hung Pan, Neha Mishra, Maaz Zuhayra, Marlies Marx, Maren Paulsen, Anne Strigli, Claudio Conrad, Dörthe Schuldt, Anupam Sinha, Henriette Ebsen, Sabin-Christin Kornell, Susanna Nikolaus, Alexander Arlt, Dieter Kabelitz, Mark Ellrichmann, Ulf Lützen, Philip C Rosenstiel, Andre Franke, Stefan Schreiber

Gut Jan 2019, 68 (1) 25-39; DOI: 10.1136/gutjnl-2018-316023
Integrin a6 loss promotes colitis-associated colorectal cancer. Response to: “Integrin a6 variants and colorectal cancer” by Beaulieu JF
Adèle De Arcangelis, Mathias Chamaillard, Patricia Simon-Assmann, Michel Labouesse

Gut Dec 2018, 67 (12) 2227-2228; DOI: 10.1136/gutjnl-2017-315727
Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn’s disease: report of the OPERA study
William J Sandborn, Scott D Lee, Dino Tarabar, Edouard Louis, Maria Klopocka, Jochen Klaus, Walter Reinisch, Xavier Hébuterne, Dong-Il Park, Stefan Schreiber, Satyaprakash Nayak, Alaa Ahmad, Anindita Banerjee, Lisa S Brown, Fabio Cataldi, Kenneth J Gorelick, John B Cheng, Mina Hassan-Zahraee, Robert Clare, Geert R D’Haens

Gut Oct 2018, 67 (10) 1824-1835; DOI: 10.1136/gutjnl-2016-313457
Integrin Î±6 variants and colorectal cancer
Jean-François Beaulieu

Gut Sep 2018, 67 (9) 1747-1748; DOI: 10.1136/gutjnl-2017-315415
Blockade of αEβ7 integrin suppresses accumulation of CD8⁺ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo
Sebastian Zundler, Daniela Schillinger, Anika Fischer, Raja Atreya, Rocío López-Posadas, Alastair Watson, Clemens Neufert, Imke Atreya, Markus F Neurath

Gut Nov 2017, 66 (11) 1936-1948; DOI: 10.1136/gutjnl-2016-312439
Hemidesmosome integrity protects the colon against colitis and colorectal cancer
Adèle De Arcangelis, Hussein Hamade, Fabien Alpy, Sylvain Normand, Emilie Bruyère, Olivier Lefebvre, Agnès Méchine-Neuville, Stéphanie Siebert, Véronique Pfister, Patricia Lepage, Patrice Laquerriere, Doulaye Dembele, Anne Delanoye-Crespin, Sophie Rodius, Sylvie Robine, Michèle Kedinger, Isabelle Van Seuningen, Patricia Simon-Assmann, Mathias Chamaillard, Michel Labouesse, Elisabeth Georges-Labouesse

Gut Oct 2017, 66 (10) 1748-1760; DOI: 10.1136/gutjnl-2015-310847
The urokinase plasminogen activator receptor (uPAR) controls macrophage phagocytosis in intestinal inflammation
Marco Genua, Silvia D'Alessio, Javier Cibella, Alessandro Gandelli, Emanuela Sala, Carmen Correale, Antonino Spinelli, Vincenzo Arena, Alberto Malesci, Sergio Rutella, Victoria A Ploplis, Stefania Vetrano, Silvio Danese

Gut Apr 2015, 64 (4) 589-600; DOI: 10.1136/gutjnl-2013-305933

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