integrins

Deciphering the vedolizumab dosing conundrum in IBD: when less is more
Timon Erik Adolph, Britta Siegmund

Gut Sep 2021, gutjnl-2021-325893; DOI: 10.1136/gutjnl-2021-325893
β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the α_Vβ6 integrin receptor
Patrick Weil, Rhea van den Bruck, Thomas Ziegenhals, Stefan Juranek, Daniel Goedde, Valerie Orth, Stefan Wirth, Andreas C Jenke, Jan Postberg

Gut Jul 2020, 69 (7) 1359-1361; DOI: 10.1136/gutjnl-2019-319015
Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances
Sebastian Zundler, Emily Becker, Lisa Lou Schulze, Markus F Neurath

Gut Sep 2019, 68 (9) 1688-1700; DOI: 10.1136/gutjnl-2018-317977
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Sebastian Zeissig, Elisa Rosati, C Marie Dowds, Konrad Aden, Johannes Bethge, Berenice Schulte, Wei Hung Pan, Neha Mishra, Maaz Zuhayra, Marlies Marx, Maren Paulsen, Anne Strigli, Claudio Conrad, Dörthe Schuldt, Anupam Sinha, Henriette Ebsen, Sabin-Christin Kornell, Susanna Nikolaus, Alexander Arlt, Dieter Kabelitz, Mark Ellrichmann, Ulf Lützen, Philip C Rosenstiel, Andre Franke, Stefan Schreiber

Gut Jan 2019, 68 (1) 25-39; DOI: 10.1136/gutjnl-2018-316023
Mechanism of action of vedolizumab: do we really understand it?
Gerhard Rogler

Gut Jan 2019, 68 (1) 4-5; DOI: 10.1136/gutjnl-2018-316777
Integrin a6 loss promotes colitis-associated colorectal cancer. Response to: “Integrin a6 variants and colorectal cancer” by Beaulieu JF
Adèle De Arcangelis, Mathias Chamaillard, Patricia Simon-Assmann, Michel Labouesse

Gut Dec 2018, 67 (12) 2227-2228; DOI: 10.1136/gutjnl-2017-315727
Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn’s disease: report of the OPERA study
William J Sandborn, Scott D Lee, Dino Tarabar, Edouard Louis, Maria Klopocka, Jochen Klaus, Walter Reinisch, Xavier Hébuterne, Dong-Il Park, Stefan Schreiber, Satyaprakash Nayak, Alaa Ahmad, Anindita Banerjee, Lisa S Brown, Fabio Cataldi, Kenneth J Gorelick, John B Cheng, Mina Hassan-Zahraee, Robert Clare, Geert R D’Haens

Gut Oct 2018, 67 (10) 1824-1835; DOI: 10.1136/gutjnl-2016-313457
Integrin Î±6 variants and colorectal cancer
Jean-François Beaulieu

Gut Sep 2018, 67 (9) 1747-1748; DOI: 10.1136/gutjnl-2017-315415
Blockade of αEβ7 integrin suppresses accumulation of CD8⁺ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo
Sebastian Zundler, Daniela Schillinger, Anika Fischer, Raja Atreya, Rocío López-Posadas, Alastair Watson, Clemens Neufert, Imke Atreya, Markus F Neurath

Gut Nov 2017, 66 (11) 1936-1948; DOI: 10.1136/gutjnl-2016-312439
Hemidesmosome integrity protects the colon against colitis and colorectal cancer
Adèle De Arcangelis, Hussein Hamade, Fabien Alpy, Sylvain Normand, Emilie Bruyère, Olivier Lefebvre, Agnès Méchine-Neuville, Stéphanie Siebert, Véronique Pfister, Patricia Lepage, Patrice Laquerriere, Doulaye Dembele, Anne Delanoye-Crespin, Sophie Rodius, Sylvie Robine, Michèle Kedinger, Isabelle Van Seuningen, Patricia Simon-Assmann, Mathias Chamaillard, Michel Labouesse, Elisabeth Georges-Labouesse

Gut Oct 2017, 66 (10) 1748-1760; DOI: 10.1136/gutjnl-2015-310847

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