mucosal immunology

ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo
Anja Schulz-Kuhnt, Katharina Rühle, Asal Javidmehr, Michael Döbrönti, Jana Biwank, Selina Knittel, Peter Neidlinger, Jannik Leupold, Li-Juan Liu, Mark Dedden, Regina Verena Taudte, Arne Gessner, Martin F Fromm, Dirk Mielenz, Lucas Kreiss, Maximilian J Waldner, Sebastian Schürmann, Oliver Friedrich, Barbara Dietel, Rocío López-Posadas, Christina Plattner, The TRR241 IBDome Consortium, Sebastian Zundler, Christoph Becker, Raja Atreya, Markus F Neurath, Imke Atreya

Gut Apr 2024, 73 (4) 601-612; DOI: 10.1136/gutjnl-2023-330543
Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice
Tim Hendrikx, Sonja Lang, Dragana Rajcic, Yanhan Wang, Sara McArdle, Kenneth Kim, Zbigniew Mikulski, Bernd Schnabl

Gut Oct 2023, 72 (10) 1959-1970; DOI: 10.1136/gutjnl-2022-328265
MCPIP1 restrains mucosal inflammation by orchestrating the intestinal monocyte to macrophage maturation via an ATF3-AP1S2 axis
Huiying Lu, Cui Zhang, Wei Wu, Huimin Chen, Ritian Lin, Ruicong Sun, Xiang Gao, Gengfeng Li, Qiong He, Han Gao, Xiaohan Wu, Jian Lin, Ruixin Zhu, Jianli Niu, Pappachan E Kolattukudy, Zhanju Liu

Gut May 2023, 72 (5) 882-895; DOI: 10.1136/gutjnl-2022-327183
A novel unconventional T cell population enriched in Crohn’s disease
Elisa Rosati, Gabriela Rios Martini, Mikhail V Pogorelyy, Anastasia A Minervina, Frauke Degenhardt, Mareike Wendorff, Soner Sari, Gabriele Mayr, Antonella Fazio, Christel Marie Dowds, Charlotte Hauser, Florian Tran, Witigo von Schönfels, Julius Pochhammer, Maria A Salnikova, Charlot Jaeckel, Johannes Boy Gigla, Sanaz Sedghpour Sabet, Matthias Hübenthal, Esther Schiminsky, Stefan Schreiber, Philip C Rosenstiel, Alexander Scheffold, Paul G Thomas, Wolfgang Lieb, Bernd Bokemeyer, Maria Witte, Konrad Aden, Alexander Hendricks, Clemens Schafmayer, Jan-Hendrick Egberts, Ilgar Z Mamedov, Petra Bacher, Andre Franke

Gut Nov 2022, 71 (11) 2194-2204; DOI: 10.1136/gutjnl-2021-325373
Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence
Marianne Rebecca Spalinger, Ali Shawki, Pritha Chatterjee, Vinicius Canale, Alina Santos, Anica Sayoc-Becerra, Michael Scharl, Michel L Tremblay, James Borneman, Declan F McCole

Gut Jan 2022, 71 (1) 89-99; DOI: 10.1136/gutjnl-2020-323636
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance
Dominik Aschenbrenner, Maria Quaranta, Soumya Banerjee, Nicholas Ilott, Joanneke Jansen, Boyd Steere, Yin-Huai Chen, Stephen Ho, Karen Cox, Carolina V Arancibia-Cárcamo, Mark Coles, Eamonn Gaffney, Simon PL Travis, Lee Denson, Subra Kugathasan, Jochen Schmitz, Fiona Powrie, Stephen N Sansom, Holm H Uhlig

Gut Jun 2021, 70 (6) 1023-1036; DOI: 10.1136/gutjnl-2020-321731
Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma
Paolo Carrega, Paola Orecchia, Linda Quatrini, Nicola Tumino, Roberta Venè, Roberto Benelli, Alessandro Poggi, Stefano Scabini, Maria Cristina Mingari, Lorenzo Moretta, Paola Vacca

Gut Dec 2020, 69 (12) 2261-2263; DOI: 10.1136/gutjnl-2020-320908
CD177⁺ neutrophils as functionally activated neutrophils negatively regulate IBD
Guangxi Zhou, Lin Yu, Leilei Fang, Wenjing Yang, Tianming Yu, Yinglei Miao, Minhu Chen, Kaichun Wu, Feidi Chen, Yingzi Cong, Zhanju Liu

Gut Jun 2018, 67 (6) 1052-1063; DOI: 10.1136/gutjnl-2016-313535
Secretion imbalance between tumour necrosis factor and its inhibitor in inflammatory bowel disease
M Noguchi, N Hiwatashi, Z Liu, T Toyota

Gut Aug 1998, 43 (2) 203-209; DOI: 10.1136/gut.43.2.203
Expansion of IL-23 receptor bearing TNFR2+ T cells is associated with molecular resistance to anti-TNF therapy in Crohn’s disease
Heike Schmitt, Ulrike Billmeier, Walburga Dieterich, Timo Rath, Sophia Sonnewald, Stephen Reid, Simon Hirschmann, Kai Hildner, Maximilian J Waldner, Jonas Mudter, Arndt Hartmann, Robert Grützmann, Clemens Neufert, Tino Münster, Markus F Neurath, Raja Atreya

Gut May 2019, 68 (5) 814-828; DOI: 10.1136/gutjnl-2017-315671

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