pancreatic cancer

Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion
Hong Jiang, Xiuting Liu, Brett L Knolhoff, Samarth Hegde, Kyung Bae Lee, Hongmei Jiang, Ryan C Fields, Jonathan A Pachter, Kian-Huat Lim, David G DeNardo

Gut Jan 2020, 69 (1) 122-132; DOI: 10.1136/gutjnl-2018-317424
Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures
Aatur D Singhi, Marina N Nikiforova, Jennifer Chennat, Georgios I Papachristou, Asif Khalid, Mordechai Rabinovitz, Rohit Das, Savreet Sarkaria, M Samir Ayasso, Abigail I Wald, Sara E Monaco, Michael Nalesnik, N Paul Ohori, David Geller, Allan Tsung, Amer H Zureikat, Herbert Zeh, J Wallis Marsh, Melissa Hogg, Kenneth Lee, David L Bartlett, James F Pingpank, Abhinav Humar, Nathan Bahary, Anil K Dasyam, Randall Brand, Kenneth E Fasanella, Kevin McGrath, Adam Slivka

Gut Jan 2020, 69 (1) 52-61; DOI: 10.1136/gutjnl-2018-317817
Targeting tumour microenvironment, a FAKtual challenge in pancreatic cancer
Ezequiel J Tolosa, Martín E Fernández-Zapico

Gut Jan 2020, 69 (1) 1-2; DOI: 10.1136/gutjnl-2019-318962
GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca²⁺ signalling in a GABA-independent manner
Shu-Heng Jiang, Li-Li Zhu, Man Zhang, Rong-Kun Li, Qin Yang, Jiang-Yu Yan, Ce Zhang, Jian-Yu Yang, Fang-Yuan Dong, Miao Dai, Li-Peng Hu, Jun Li, Qing Li, Ya-Hui Wang, Xiao-Mei Yang, Yan-Li Zhang, Hui-Zhen Nie, Lei Zhu, Xue-Li Zhang, Guang-Ang Tian, Xiao-Xin Zhang, Xiao-Yan Cao, Ling-Ye Tao, Shan Huang, Yong-Sheng Jiang, Rong Hua, Kathy Qian Luo, Jian-Ren Gu, Yong-Wei Sun, Shangwei Hou, Zhi-Gang Zhang

Gut Nov 2019, 68 (11) 1994-2006; DOI: 10.1136/gutjnl-2018-317479
Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis
Simone Benitz, Tobias Straub, Ujjwal Mukund Mahajan, Jurik Mutter, Stefan Czemmel, Tatjana Unruh, Britta Wingerath, Sabrina Deubler, Lisa Fahr, Tao Cheng, Sven Nahnsen, Philipp Bruns, Bo Kong, Susanne Raulefs, Güralp O Ceyhan, Julia Mayerle, Katja Steiger, Irene Esposito, Jörg Kleeff, Christoph W Michalski, Ivonne Regel

Gut Nov 2019, 68 (11) 2007-2018; DOI: 10.1136/gutjnl-2018-317208
DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth
Jeroni Luna, Jacopo Boni, Miriam Cuatrecasas, Xavier Bofill-De Ros, Estela Núñez-Manchón, Meritxell Gironella, Eva C Vaquero, Maria L Arbones, Susana de la Luna, Cristina Fillat

Gut Aug 2019, 68 (8) 1465-1476; DOI: 10.1136/gutjnl-2018-316128
ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas
Wenjia Wang, Scott C Friedland, Bing Guo, Michael R O’Dell, William B Alexander, Christa L Whitney-Miller, Diana Agostini-Vulaj, Aaron R Huber, Jason R Myers, John M Ashton, Richard F Dunne, Laurie A Steiner, Aram F Hezel

Gut Jul 2019, 68 (7) 1245-1258; DOI: 10.1136/gutjnl-2017-315541
SWI/SNF component ARID1A restrains pancreatic neoplasia formation
Sam C Wang, Ibrahim Nassour, Shu Xiao, Shuyuan Zhang, Xin Luo, Jeon Lee, Lin Li, Xuxu Sun, Liem H Nguyen, Jen-Chieh Chuang, Lan Peng, Scott Daigle, Jeanne Shen, Hao Zhu

Gut Jul 2019, 68 (7) 1259-1270; DOI: 10.1136/gutjnl-2017-315490
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming
Marina Koutsioumpa, Maria Hatziapostolou, Christos Polytarchou, Ezequiel J Tolosa, Luciana L Almada, Swapna Mahurkar-Joshi, Jennifer Williams, Ana Belen Tirado-Rodriguez, Sara Huerta-Yepez, Dimitrios Karavias, Helen Kourea, George A Poultsides, Kevin Struhl, David W Dawson, Timothy R Donahue, Martín E Fernández-Zapico, Dimitrios Iliopoulos

Gut Jul 2019, 68 (7) 1271-1286; DOI: 10.1136/gutjnl-2017-315690
Chromatin remodelling controls pancreatic tissue fate
Elisabeth Hessmann, Volker Ellenrieder

Gut Jul 2019, 68 (7) 1139-1140; DOI: 10.1136/gutjnl-2018-317486

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