TNF

Robust SARS-CoV-2 antibody and T cell immunity following three COVID-19 vaccine doses in inflammatory bowel disease patients receiving anti-TNF or alternative treatments
Eva Zhang, Thi H O Nguyen, Lilith F Allen, Lukasz Kedzierski, Louise C Rowntree, So Young Chang, Wuji Zhang, Jennifer R Habel, Isabelle J Foo, Tejas Menon, Jeni Mitchell, Rupert W Leong, Katherine Bond, Deborah A Williamson, Katherine Kedzierska, Britt Christensen

Gut Apr 2024, 73 (4) 712-714; DOI: 10.1136/gutjnl-2022-329136
Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease
Li Zuo, Wei-Ting Kuo, Feng Cao, Sandra D Chanez-Paredes, Daniel Zeve, Prabhath Mannam, Léa Jean-François, Anne Day, W Vallen Graham, Yan Y Sweat, Nitesh Shashikanth, David T Breault, Jerrold R Turner

Gut May 2023, 72 (5) 870-881; DOI: 10.1136/gutjnl-2021-326534
Emerging treatment options for extraintestinal manifestations in IBD
Thomas Greuter, Florian Rieder, Torsten Kucharzik, Laurent Peyrin-Biroulet, Alain M Schoepfer, David T Rubin, Stephan R Vavricka

Gut Apr 2021, 70 (4) 796-802; DOI: 10.1136/gutjnl-2020-322129
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD
Nicholas A Kennedy, Simeng Lin, James R Goodhand, Neil Chanchlani, Benjamin Hamilton, Claire Bewshea, Rachel Nice, Desmond Chee, JR Fraser Cummings, Aileen Fraser, Peter M Irving, Nikolaos Kamperidis, Klaartje B Kok, Christopher Andrew Lamb, Jonathan Macdonald, Shameer Mehta, Richard CG Pollok, Tim Raine, Philip J Smith, Ajay Mark Verma, Simon Jochum, Timothy J McDonald, Shaji Sebastian, Charlie W Lees, Nick Powell, Tariq Ahmad

Gut Oct 2021, 70 (10) 1884-1893; DOI: 10.1136/gutjnl-2021-324789
Addition of azathioprine to the switch of anti-TNF in patients with IBD in clinical relapse with undetectable anti-TNF trough levels and antidrug antibodies: a prospective randomised trial
Xavier Roblin, Nicolas Williet, Gilles Boschetti, Jean-Marc Phelip, Emilie Del Tedesco, Anne-Emmanuelle Berger, Philippe Vedrines, Gerard Duru, Laurent Peyrin-Biroulet, Stéphane Nancey, Bernard Flourie, Stephane Paul

Gut Jul 2020, 69 (7) 1206-1212; DOI: 10.1136/gutjnl-2019-319758
Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling
Pim J Koelink, Felicia M Bloemendaal, Bofeng Li, Liset Westera, Esther W M Vogels, Manon van Roest, Anouk K Gloudemans, Angelique B van 't Wout, Hannelie Korf, Séverine Vermeire, Anje A te Velde, Cyriel Y Ponsioen, Geert RAM D'Haens, J Sjef Verbeek, Terrence L Geiger, Manon E Wildenberg, Gijs R van den Brink

Gut Jun 2020, 69 (6) 1053-1063; DOI: 10.1136/gutjnl-2019-318264
Life is fragile: FMRP controls cell death in liver disease
Mihael Vucur, Tom Luedde

Gut Jan 2020, 69 (1) 2-3; DOI: 10.1136/gutjnl-2019-319534
Expansion of IL-23 receptor bearing TNFR2+ T cells is associated with molecular resistance to anti-TNF therapy in Crohn’s disease
Heike Schmitt, Ulrike Billmeier, Walburga Dieterich, Timo Rath, Sophia Sonnewald, Stephen Reid, Simon Hirschmann, Kai Hildner, Maximilian J Waldner, Jonas Mudter, Arndt Hartmann, Robert Grützmann, Clemens Neufert, Tino Münster, Markus F Neurath, Raja Atreya

Gut May 2019, 68 (5) 814-828; DOI: 10.1136/gutjnl-2017-315671
Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial
Casper Steenholdt, Jørn Brynskov, Ole Østergaard Thomsen, Lars Kristian Munck, Jan Fallingborg, Lisbet Ambrosius Christensen, Gitte Pedersen, Jens Kjeldsen, Bent Ascanius Jacobsen, Anne Sophie Oxholm, Jakob Kjellberg, Klaus Bendtzen, Mark Andrew Ainsworth

Gut Jun 2014, 63 (6) 919-927; DOI: 10.1136/gutjnl-2013-305279
The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease
Niels Vande Casteele, Reena Khanna, Barrett G Levesque, Larry Stitt, G Y Zou, Sharat Singh, Steve Lockton, Scott Hauenstein, Linda Ohrmund, Gordon R Greenberg, Paul J Rutgeerts, Ann Gils, William J Sandborn, Séverine Vermeire, Brian G Feagan

Gut Oct 2015, 64 (10) 1539-1545; DOI: 10.1136/gutjnl-2014-307883

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