Summary
Two cases of necrotising enterocolitis with perforation occurred in patients with paralytic ileus after loperamide therapy. The possible role of loperamide in the pathogenesis of the complications is suggested.
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Olm, M., Gonzalez, F.J., Garcia-Valdecasas, J.C. et al. Necrotising colitis with perforation in diarrhoic patients treated with loperamide. Eur J Clin Pharmacol 40, 415–416 (1991). https://doi.org/10.1007/BF00265854
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DOI: https://doi.org/10.1007/BF00265854