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Colonic mucosal pH in humans

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Abstract

Mucosal pH was measured at specific anatomic segments within the colon using a flexible pH probe in patients prepared for colonoscopy. The data revealed similar pH measurements along the length of the colon, irrespective of the presence or absence of colorectal neoplasia. Patients exhibited a relatively acidic right colon; a more alkaline transverse, left, and sigmoid colon; and a relatively acidic rectum. There were no apparent genderor age-related effects on colonic mucosal pH.

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Authors and Affiliations

  1. Departments of Medicine and Surgery, Cornell University Medical College, 525 East 68 Street, Room F-231, 10021, New York, New York

    Carl J. McDougall MD, Ronald Wong MD, Peter Scudera MD, Martin Lesser PhD & Jerome J. DeCosse PhD, MD

  2. Division of Biostatistics at North Shore University Hospital-Cornell University Medical College, 525 East 68 Street, Room F-231, 10021, New York, New York

    Carl J. McDougall MD, Ronald Wong MD, Peter Scudera MD, Martin Lesser PhD & Jerome J. DeCosse PhD, MD

Authors
  1. Carl J. McDougall MD
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  2. Ronald Wong MD
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  3. Peter Scudera MD
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  4. Martin Lesser PhD
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  5. Jerome J. DeCosse PhD, MD
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McDougall, C.J., Wong, R., Scudera, P. et al. Colonic mucosal pH in humans. Digest Dis Sci 38, 542–545 (1993). https://doi.org/10.1007/BF01316512

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  • DOI: https://doi.org/10.1007/BF01316512

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