Summary
Four hours after hemorrhagic necrotizing pancreatitis was induced in experimental animals the concentration of lysolecithin in pancreatic tissue rose (p=0.0025). Parenteral administration of unspecific inhibitors of phospholipase A2, such as chlorpromazine, gabexat mesilat and CaNa2 EDTA, can neither inhibit elevation of the enzyme nor influence the course of the disease.
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Kahle, M., König, H. & Filler, R.D. Lysolecithin concentration in pancreatic tissue during therapy with phospholipase A2-inhibitors in acute necrotizing pancreatitis. Klin Wochenschr 67, 177–179 (1989). https://doi.org/10.1007/BF01711348
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DOI: https://doi.org/10.1007/BF01711348