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Sclerosing cholangitis: Broad spectrum of radiographic features

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Abstract

The broad spectrum of radiographic appearance of sclerosing cholangitis is illustrated in 19 cases. A classification of intrahepatic and extrahepatic features is presented, based on extent of narrowing of bile ducts, severity of narrowing, contour abnormalities, and presence of postsclerotic dilatation. In 13 of 19 cases, both intra- and extrahepatic ducts were involved. The most common form of intrahepatic involvement (8/19) was irregular stenosis obliterating peripheral ducts leaving only the more central ducts filled with contrast material. The most common type of extrahepatic duct involvement was a well-defined segment of either smooth or irregular narrowing. The most extensive involvement of intrahepatic ducts was often associated with more well-defined, less extensive extrahepatic duct involvement. In 7 patients, radiographic features were evaluated over periods ranging from several months to several years. Intrahepatic duct involvement either remained unchanged or worsened, while extrahepatic features more often remained unchanged. Our classification of patterns of involvement was applied to previous reports and revealed frequency of type of duct involvement similar to our series.

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References

  1. Bartholomew LG, Cain JC, Woolner LB, Utz DC, Ferris DO: Sclerosing cholangitis, its possible association with Riedel's struma and fibrosis retroperitonitis.N Engl J Med 269:8–12, 1963

    PubMed  Google Scholar 

  2. Albo RJ, Obata WG: Radiologic diagnosis of primary sclerosing cholangitis.Radiology 81:123–125, 1963

    PubMed  Google Scholar 

  3. Smoth MP, Loe RH: Sclerosing cholangitis: review of recent case reports and associated disease and four new cases.Am J Surg 110:239–245, 1965

    PubMed  Google Scholar 

  4. Warren KW, Athanassiades S, Monge JI: Primary sclerosing cholangitis. A study of forty-two cases.Am J Surg 111:23–28, 1966

    PubMed  Google Scholar 

  5. Thorpe MEC, Scheuer PJ, Sherlock S: Primary sclerosing cholangitis, the biliary tree and ulcerative colitis.Gut 8:435–448, 1967

    PubMed  Google Scholar 

  6. Cutler B, Donaldson GA: Primary sclerosing cholangitis and obliterative cholangitis.Am J Surg 117:502–511, 1969

    PubMed  Google Scholar 

  7. Myers RN, Cooper JH, Padia N: Primary sclerosing cholangitis complete gross and histologic reversal after longterm steroid therapy.Am J Gastroenterol 53:527–538, 1970

    PubMed  Google Scholar 

  8. Krieger J, Seaman WB, Porter MR: The roentgenologic appearance of sclerosing cholangitis.Radiology 95:369–375, 1970

    PubMed  Google Scholar 

  9. Manesis JG, Sullivan JF: Primary sclerosing cholangitis.Arch Intern Med 115:137–139, 1965

    PubMed  Google Scholar 

  10. Elias E, Summerfield JA, Dick R, Sherlock S: Endoscopic retrograde cholangiopancreatography in the diagnosis of jaundice associated with ulcerative colitis.Gastroenterology 67:907–911, 1974

    PubMed  Google Scholar 

  11. Rogers JV Jr, Copeland AJ Jr, Schroder FS, Amerson JR: Sclerosing cholangitis, roentgenographic features.South Med J 65:587–594, 1972

    PubMed  Google Scholar 

  12. Abbruzzese AA: Retrograde cholangiography and sclerosing cholangitis,Am J Dig Dis 19:571–574, 1974

    PubMed  Google Scholar 

  13. Oviedo MA, Volkmer D, Scanlon EF: Sclerosing cholangitis.Arch Surg 109:747–749, 1974

    PubMed  Google Scholar 

  14. Danzi JT, Makipour H, Farmer RC: Primary sclerosing cholangitis, a report of 9 cases and clinical review.Am J Gastroenterol 65:109–120, 1976

    PubMed  Google Scholar 

  15. Fee HJ, Gerwitz H, Schiller J, Longmire WP: Sclerosing cholangitis and primary biliary cirrhosis, a disease spectrum?Ann Surg 186:589–593, 1977

    PubMed  Google Scholar 

  16. Rohrmann CA Jr, Ansel HJ, Ayoola EA, Silvis SE, Vennes JA: Endoscopie retrograde intrahepatic cholangiogram radiographie findings in intrahepatic disease.AJR 128:45–52, 1977

    PubMed  Google Scholar 

  17. Rohrmann CA Jr, Ansel HJ, Freeny PC, Silverstein FE, Protell RL, Fenster LF, Ball T, Vennes JA, Silvis SE: Cholangiographic abnormalities in patients with inflammatory bowel disease.Radiology 127:635–641, 1978

    PubMed  Google Scholar 

  18. Chapman RWG, Marborgh BA, Rhodes JM, Summerfield JA, Dick R, Scheuer, PJ, Sherlock S: Primary sclerosing cholangitis, a review of its clinical features, cholangiography and hepatic histology.Gut 21:870–877, 1980

    PubMed  Google Scholar 

  19. Wiesner RH, LaRusso NF: Clinicopatholgic features of the syndrome of primary sclerosing cholangitis.Gastoenterology 79:200–206, 1980

    Google Scholar 

  20. Wood RAB, Cushieri A: Is sclerosing cholangitis complicating ulcerative colitis a reversible condition?Lancet 2:716–718, 1980

    PubMed  Google Scholar 

  21. Martin EC, Fankuchen E, Schultz RW, Casarella WJ: Percutaneous dilatation in primary sclerosing cholangitis.AJR 137:603–605, 1981

    PubMed  Google Scholar 

  22. Chapman RWG, Burrough AK, Sherlock S: Longstanding asymptomatic primary sclerosing cholangitis, report of 3 cases.Dig Dis Sci 26:778–782, 1981

    PubMed  Google Scholar 

  23. Stewart ET, Vennes JA, Greenen JE (eds):Atlas of Endoscopie Retrograde Cholangiopancreatography. St. Louis: Mosby, 1977

    Google Scholar 

  24. Spivak W, Grand RJ, Eraklis A: A case of primary sclerosing cholangitis in childhood.Gastroenterology 82:129–132, 1982

    PubMed  Google Scholar 

  25. Goldberg HI, Bilboa MK, Stewart ET, Rohrmann CA, Moss AA: Endoscopie retrograde cholangiopancreatography: radiographie technique.Am J Dig Dis 21:270–278, 1976

    PubMed  Google Scholar 

  26. Summerfield JA, Elias E, Hungerford GD, Nikapota B, Dick R, Sherlock S: The biliary system in primary biliary cirrhosis, a study by endoscopie retrograde cholangiopancreatography.Gastroenterology 70:240–243, 1976

    PubMed  Google Scholar 

  27. Fleming MD, Carlson HC, Adson MA: Percutaneous transhepatic cholangiography, the differential diagnosis of bile duct pathology.AJR 116:327–336, 1972

    Google Scholar 

  28. Whelton MJ: Sclerosing cholangitis.Clin Gastroenterol 2:163–173, 1973

    PubMed  Google Scholar 

  29. Kessler RE, Falkenstein DB, Clemett AR, Zimmon DS: Indications, clinical value and complications of endoscopic retrograde cholangiopancreatography.Surg Gynecol Obstet 142:865–870, 1976

    PubMed  Google Scholar 

  30. Clemett AR: Carcinoma of the major bile ducts.Radiology 84:894–903, 1965

    PubMed  Google Scholar 

  31. Bathal PS, Powell LW: Primary intrahepatic obliterating cholangitis: a possible variant of “sclerosing cholangitis”.Gut 10:886–893, 1969

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, 2nd Hospital, China Medical College, Shen-Yang, Liaoning, People's Republic of China

    Chen Li-Yeng

  2. Department of Radiology, University of California, 94143, San Francisco, CA, USA

    Henry I. Goldberg

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  1. Chen Li-Yeng
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  2. Henry I. Goldberg
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Li-Yeng, C., Goldberg, H.I. Sclerosing cholangitis: Broad spectrum of radiographic features. Gastrointest Radiol 9, 39–47 (1984). https://doi.org/10.1007/BF01887799

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  • DOI: https://doi.org/10.1007/BF01887799

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