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Self-expandable metallic stent placement for patients with inoperable esophageal carcinoma: investigation of the influence of prior radiotherapy and chemotherapy

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Abstract

Purpose

The aim of this study was to evaluate the efficacy and complications of self-expandable metallic stent placement for patients with inoperable esophageal carcinoma after radiotherapy and/or chemotherapy.

Materials and methods

We obtained data from 19 patients with advanced or recurrent esophageal carcinoma between 1996 and 2000. In all patients, a self-expandable metallic stent was placed under fluoroscopic guidance. Dysphagia before and after stent placement was graded. Complications after stent placement were also evaluated. Data were compared between patients with and without prior radiotherapy and/or chemotherapy.

Results

The procedure was technically successful in all but one patient. The dysphagia grade improved in all patients. No life-threatening complications occurred. The other major complications such as mediastinitis occurred in two patients, and pneumonia and funnel phenomenon occurred in one patient each. These patients had a history of radiotherapy and/or chemotherapy prior to stent placement. Eight of the twelve patients with prior radiotherapy and/or chemotherapy compared with one of seven patients without prior therapy had persistent chest pain, which was a statistically significant difference (P < 0.05).

Conclusion

Placement of self-expandable metallic stents was effective for patients with advanced or recurrent esophageal carcinoma. However, prior irradiation and/or chemotherapy increased the risk of persistent chest pain after stent placement.

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Author notes

  1. Noboru Tanigawa

    Present address: Department of Radiology, Kansai Medical University, Moriguchi, Osaka, Japan

Authors and Affiliations

  1. Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207 Uehara, Nishihara-cho, Nakagami-gun, Okinawa, 903-0215, Japan

    Yuko Iraha, Sadayuki Murayama, Takafumi Toita, Takashi Utsunomiya, Osamu Nagata, Tamaki Akamine, Kazuhiko Ogawa, Genki Adachi & Noboru Tanigawa

Authors
  1. Yuko Iraha
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  2. Sadayuki Murayama
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  3. Takafumi Toita
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  4. Takashi Utsunomiya
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  5. Osamu Nagata
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  6. Tamaki Akamine
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  7. Kazuhiko Ogawa
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  8. Genki Adachi
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  9. Noboru Tanigawa
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Corresponding author

Correspondence to Sadayuki Murayama.

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Iraha, Y., Murayama, S., Toita, T. et al. Self-expandable metallic stent placement for patients with inoperable esophageal carcinoma: investigation of the influence of prior radiotherapy and chemotherapy. Radiat Med 24, 247–252 (2006). https://doi.org/10.1007/s11604-005-1539-8

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  • DOI: https://doi.org/10.1007/s11604-005-1539-8

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