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The Association of Immune Cell Infiltration and Prognosis in Colorectal Cancer

Current Colorectal Cancer Reports

Abstract

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. The tumor microenvironment is of great biological importance in cancer development and progression and harbors several different immune cells representing both the innate and the adaptive immune response. These inflammatory cells may have both tumor-promoting and tumor-suppressing effects, and they have been shown to be of prognostic importance. This review summarizes the recent evidence regarding the prognostic significance of the host response to colorectal cancer.

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Richard Palmqvist has received financial support through research grants from the Swedish Cancer Society and the Swedish Research Council.

Maria L. Wikberg and Agnes Ling declare that they have no conflict of interest.

Sofia Edin has received financial support through a research grant from the Cancer Research Foundation in Northern Sweden.

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Palmqvist, R., Wikberg, M.L., Ling, A. et al. The Association of Immune Cell Infiltration and Prognosis in Colorectal Cancer. Curr Colorectal Cancer Rep 9, 372–379 (2013). https://doi.org/10.1007/s11888-013-0192-3

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