Elsevier

Clinica Chimica Acta

Volume 33, Issue 2, July 1971, Pages 317-324
Clinica Chimica Acta

Albumine, igg et iga dans le suc pancréatique humain normal chez l'adulteAlbumin, IgG and, IgA in Normal Human Pancreatic Juice

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Abstract

Normal human pancreatic juice was collected by catheterisation of the main pancreatic duct in 5 adult subjects of two sexes. On these samples containing proteolytic enzymes in the zymogen form, we found and quantitated albumin, IgG and IgA by the single radial immunodiffusion technique. Albumin represents 1.26 ± 0.36% (at p< 0.05) of total proteins of pancreatic juice; IgG 0.23 ± 0.039 and IgA 0.18 ± 0.034. The albumin/IgG ratio is not significantly different from that in human serum while the albumin/IgA and IgG/IgA ratios significantly differ. This fact favours the hypothesis of a local synthesis of IgA and/or a specific excretory mechanism, however this latter seems less likely.

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∗∗

Directeur Henri Sarles.

Adresse actuelle: Facultad de Medicina de Universidad Federal de Minas Gerais, BeIo-Horizonte, Minas Gerais, Brésil.

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