Research communicationMicronutrient antioxidant status in black South Africans with chronic pancreatitis: opportunity for prophylaxis
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Cited by (35)
Progressive reduction in circulating levels of carotenoids and other micronutrients in patients with chronic pancreatitis
2022, PancreatologyCitation Excerpt :More importantly, some of these differences were not only significant but also have a large effect size. Our observation of significantly lower levels of selected carotenoids, α-tocopherol, and vitamin D in CP patients than in controls was in agreement with the findings of most previous studies [19–27]. However, the present study has contributed to an improved understanding of important roles of carotenoid and vitamin status in the etiology and progression of CP for several reasons.
Pain Relief in Chronic Pancreatitis-Role of Nutritional Antioxidants
2017, Nutritional Modulators of Pain in the Aging PopulationIntake patterns of food nutrients and other substances associated with chronic pancreatitis
2013, PancreatologyCitation Excerpt :Similarly, Morris-Stiff et al. [11] demonstrated in chronic pancreatitis significantly lower plasma levels of selenium, vitamin A, vitamin E, ß-carotene, xanthine, ß-cryptoxanthine, and lycopene, when compared to controls. This reinforced inferences drawn from contemporaneous ecological studies showing an inverse relationship between the bio-availability of certain antioxidants in subjects from various populations and the prevalence of chronic pancreatitis [10,12]. These studies, however, are limited with respect to causal inference; it could reasonably be argued that low antioxidant levels are due to a state of persistent oxidative stress leading to circulatory depletion.
Pain in Chronic Pancreatitis and Pancreatic Cancer
2007, Gastroenterology Clinics of North AmericaCitation Excerpt :Antioxidant therapy has been often evaluated in the setting of CP in the international literature. This stems from the observation that levels of antioxidants, such as carotenoids, vitamins C and E, methionine, and selenium, are often deficient and reactive oxygen species are altered in patients who have CP [79–86]. Several small trials have evaluated the use of antioxidants in CP, two of which were described in the AGA technical review [87,88].