Patients with irritable bowel syndrome have greater pain tolerance than normal subjects
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Mechanisms of visceral pain in health and functional gastrointestinal disorders
2014, Scandinavian Journal of PainCitation Excerpt :It has been 35 years since it was first reported that a proportion of patients with FGIDs may display elevated pain sensitivity to experimental gut distension – visceral pain hypersensitivity (see Fig. 3) [40–43]. Whether these observed alterations in visceral sensitivity are part of a global phenomenon of generalized sensory dysfunction is controversial [36,44–46]. Visceral pain hypersensitivity has become the germane hypothesis to account for chronic pain in FGIDs.
Gastrointestinal disorders
2012, Handbook of Clinical NeurologyIncreased Auditory Startle Reflex in Children with Functional Abdominal Pain
2010, Journal of PediatricsIrritable Bowel Syndrome
2010, Current Clinical Medicine: Expert Consult Premium Edition - Enhanced Online Features and Print
This work was presented at the Annual Meeting of the American Gastroenterological Association, San Francisco, May 1986, and has been published in abstract form (Gastroenterology 1986;90:1380).
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Dr. Cook is supported by a University of Sydney Postgraduate Medical Foundation Award and a Hamilton Regional Medical Associates Scholarship.