Regular paperCalcitonin gene-related peptide neurons innervating the canine digestive system
References (34)
- et al.
Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats
Gastroenterology
(1987) - et al.
Calcitonin gene-related peptide and substance P in afferents to the upper gastrointestinal tract in the rat
Neurosci. Lett.
(1987) - et al.
Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of the guinea pig
Neurosci. Lett.
(1985) - et al.
Immunocytochemical identification of islet cells and nerve fibers containing calcitonin gene-related peptide-like immunoreactivity in the rat pancreas
Gastroenterology
(1986) - et al.
Calcitonin gene-related peptide: novel neuropeptide
Life Sci.
(1986) - et al.
Calcitonin gene-related peptide: enteric and cardiovascular effects in the dog
Gastroenterology
(1988) - et al.
Possible involvement of calcitonin gene-related peptide (CGRP) in non-cholinergic, non-adrenergic relaxation induced by mesenteric nerve stimulation in guinea pig ileum
Brain Res.
(1989) - et al.
Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans
Gastroenterology
(1988) - et al.
Calcitonin gene-related peptide immunoreactive sensory and motor nerves of the rat, cat, and monkey esophagus
Gastroenterology
(1985) - et al.
Peptidergic innervation of the human esophageal smooth muscle
Gastroenterology
(1991)
Calcitonin gene-related peptide: potent peripheral inhibitor of gastric acid secretion in rats and dogs
Gastroenterology
Dual effects of calcitonin gene-related peptide on insulin secretion in the perfused dog pancreas
Regul. Pept.
Calcitonin gene-related peptide-α receptor binding sites in the gastrointestinal tract
Neuroscience
Calcitonin gene-related peptide and somatostatin inhibit insulin release from individual rat B cells
Mol. Cell. Endocrinol.
Characterization of the peptidergic afferent innervation of the stomach in the rat, mouse and guinea-pig
Neuroscience
Dual intrinsic and extrinsic origins of CGRP- and NPY-immunoreactive nerves of rat gut and pancreas
J. Neurosci.
Calcitonin gene-related peptide-containing neurons supplying the rat digestive system: differential distribution and expression pattern
Somatosen. Mot. Res.
Cited by (43)
Dawn of a New RAMPage
2020, Trends in Pharmacological SciencesCitation Excerpt :CGRP is a neuropeptide that signals through the CGRP receptor (RAMP1–CLR) [4]. The CGRP receptor is expressed on a variety of cell types [48,49] (Figure 1A,B) and activation via CGRP results in potent vasodilation that has been clinically linked to migraine pathology [50] (Figure 1C). The successful therapeutic targeting of the CGRP receptor for the treatment of migraines is discussed in the section ‘Therapeutic Targeting of RAMP–GPCRs’.
The neuropeptide receptor subunit RAMP1 constrains the innate immune response during acute pancreatitis in mice
2019, PancreatologyCitation Excerpt :Although the CGRP-RAMP pathway has been extensively studied in inflammatory conditions like septic peritonitis, where the deficiency of the RAMP1 subunit of the CGRP-receptor led to an impaired anti-bacterial defence [19] to date little is known about its function in affecting the inflammatory reaction of acute pancreatitis. In previous studies, CGRP immunoreactivity has been detected in nerve fibres innervating the pancreas [20]. In addition, Schneider et al. [21] were able to show an improved pancreatic microcirculation and reduced inflammation in experimental acute pancreatitis after treating rats with capsaicin, a substance of red hot chili peppers inducing a release of endogenous CGRP.
Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease: CGRP in diverticular disease
2019, Autonomic Neuroscience: Basic and ClinicalCitation Excerpt :In our view, these results reflect (at least by quantitative means) CGRP involvement in distinct functional roles associated with MP and SP ganglia. In the present study, CGRP-IR nerve fibers innervated the colonic tissue as previously described in canines (Sternini et al., 1992), but different than that detailed in the human small intestine (Timmermans et al., 1992) or swine descending colon (Makowska et al., 2017; Makowska and Gonkowski, 2018). In regards that we rarely detected CGRP-IR ganglionic cells and never identified a ganglion composed solely of CGRP-IR neurons as detailed by Timmermans et al. (1992).
Distribution of vagal CGRP-immunoreactive fibers in the lower esophagus and the cardia of the stomach of the rat
2009, Journal of Chemical NeuroanatomySignalling the state of the digestive tract
2006, Autonomic Neuroscience: Basic and Clinical