News and featuresThe biology of the SCID mutation
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Cross-species transmission of gibbon and orangutan hepatitis B virus to uPA/SCID mice with human hepatocytes
2011, Virus ResearchCitation Excerpt :Some researchers have attributed this to innate immunity of SCID mice (Lin et al., 1998). SCID mice have a normal innate immune system such as monocytes and macrophages (Ansell and Bancroft, 1989) which probably plays an important role in these mice. Moreover, infection of human hepatocytes with non-human primate HBV may be difficult due to the higher infectious dose required.
A model of non-specific immunity
1994, Journal of Theoretical BiologySCID mice as immune system models
1991, Current Opinion in ImmunologyNk cell depletion and recovery in SCID mice treated with anti-NK1.1 antibody
2006, Folia Histochemica et Cytobiologica
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