Regular paperReversal of hepatorenal syndrome in four patients by peroral misoprostol (prostaglandin E1 analogue) and albumin administration☆
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Cited by (85)
Hepatorenal syndrome
2014, Nephrologie et TherapeutiqueRenal haemodynamics and function following partial portal decompression
2009, HPBCitation Excerpt :The improvement in renal perfusion with therapy in hepatorenal syndrome is related to an increase in systemic vascular resistances, a reduction of portal pressure, and the suppression of endogenous vasoconstrictor activity. Furthermore, oral misoprostol, an analogue of prostaglandin E (PGE)-1, has been reported to improve renal dysfunction in patients with cirrhosis, but its application is limited by toxicity.15 Unfortunately, these medications provide temporary rather than durable improvement of extreme renal dysfunction and, generally, are not effective in hepatorenal syndrome.
Pharmacological Treatment for Hepatorenal Syndrome
2008, Critical Care Nephrology, Second EditionPGE<inf>2</inf> alleviates kidney and liver damage, decreases plasma renin activity and acute phase response in cirrhotic rats with acute liver damage
2005, Experimental and Toxicologic PathologyRenal Failure in Adult Liver Transplant Recipients
2005, Transplantation of the LiverHepatorenal syndrome: Pathogenesis and novel pharmacological targets
2004, Current Opinion in Pharmacology
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Presented in part as an abstract in Hepatology 1988; 8: 1355.
Copyright © 1990 Published by Elsevier Ireland Ltd.