Structural basis for epidermal growth factor receptor function
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Cited by (33)
G Protein-coupled Receptors Desensitize and Down-regulate Epidermal Growth Factor Receptors in Renal Mesangial Cells
2001, Journal of Biological ChemistryCitation Excerpt :That group also showed evidence that the cleavage event involved mainly the carboxyl terminus of the EGFR and did not interfere with 125I-EGF binding. This portion of the EGFR contains three major (Tyr1068, Tyr1148, and Tyr1183) and two minor (Tyr992 and Tyr1086) autophosphorylation sites (76, 77) and binding/activation sites for phospholipase C-γ, adapter protein 2 (78), and Shc (79). The proteolytic effect of ConA on EGFR does not universally attenuate EGFR functions, however.
Bone morphogenetic protein-2 inhibits MAPK-dependent Elk-1 transactivation and DNA synthesis induced by EGF in mesangial cells
1999, Biochemical and Biophysical Research CommunicationsActions of epidermal growth factor and its receptor in the thyroid
1995, Trends in Endocrinology and MetabolismStrategy for boron neutron capture therapy against tumor cells with over-expression of the epidermal growth factor-receptor
1994, International Journal of Radiation Oncology, Biology, Physics
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