Original articleAndrogen supplementation in eugonadal men with osteoporosis—effects of 6 months of treatment on bone mineral density and cardiovascular risk factors
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2014, Artery ResearchCitation Excerpt :Moreover, the changes in mean blood pressure were negatively associated with changes in non MAP-adjusted cfPWV (β = 0.682, P < 0.05) and changes in serum testosterone levels (β = −0.646, P < 0.05) due to lifestyle modifications on stepwise multivariable linear regression analysis. Furthermore, testosterone replacement therapy has been shown to have an anti-hypertensive effect in obese men.27–29 Thus, we suggest that the increased serum testosterone levels induces the lowering of the mean blood pressure, thereby contributing to the decrease in non MBP-adjusted cfPWV.
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2012, Physical Medicine and Rehabilitation Clinics of North AmericaTestosterone Deficiency and Risk Factors in the Metabolic Syndrome: Implications for Erectile Dysfunction
2011, Urologic Clinics of North AmericaCitation Excerpt :The investigators noted that the most significant reductions occurred between 6 to 9 months. In addition, Anderson and colleagues33 reported a significant favorable change in diastolic blood pressure in men treated for 6 months with T-replacement therapy. Given the fact that the relationship between hypertension and TD is complex and poorly investigated, the limited data available still suggest that T-replacement therapy tends to normalize blood pressure; however, this remains to be investigated.
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