Selected SummariesAngiotensin II receptor antagonists in the pharmacological therapy of portal hypertension: A caution
Section snippets
Comment
Various aspects of this study deserve comment, the first one being the remarkable effect on portal pressure attained with losartan. The mean reduction in HVPG of approximately 45% is the most pronounced pharmacological effect on portal hypertension described so far in cirrhotic patients. Before this study, the greatest reduction in HVPG had been 36%, which was reported in an early study of long-term oral administration of propranolol in cirrhotic patients (Hepatology 1982;2:523-527). Subsequent
References (0)
Cited by (0)
Copyright © 1999 Published by Elsevier Inc. All rights reserved.