Endoscopic ultrasound–guided, 18-gauge, fine needle aspiration biopsy of the pancreas using a 2.8 mm channel convex array echoendoscope☆,☆☆,★
Section snippets
Patients
During a 10-month period between August 1995 and June 1996, 45 patients (mean age 62 years, range 26 to 77 years) underwent FNAB of the pancreas. Patients were selected to undergo EUS-guided FNAB on the basis of their clinical history and findings of a mass lesion on preliminary endosonographic evaluation using an Olympus 360-degree radial scanning echoendoscope (GF-UM20; Olympus Optical, Inc., Tokyo, Japan). In all patients FNAB was judged to have potential impact on treatment strategy. Before
Results
FNAB of pancreatic lesions was attempted in 45 patients. Lesions were located in the head in 28 patients, the body in 12 patients, and the tail of the pancreas in 5 patients. In 5 patients the needle failed to penetrate indurated lesions despite repeated attempts using different sites and angles to access the lesion. Four of these five patients subsequently underwent surgery; the surgical pathology demonstrated chronic calcifying pancreatitis in two patients and malignancy associated with
Discussion
Several studies have reported on EUS-guided aspiration to obtain tissue specimens for cytologic diagnosis of pancreatic lesions.1, 2, 3, 4, 5 The investigators in these studies used 22- or 25-gauge needles that were inserted through the 2.0 mm working channel of the Pentax FG 32 UA convex array echoendoscope. The reported yield for adequate cytologic specimens has ranged from 82% to 91%. Two studies1, 3 mentioned that core biopsy specimens were occasionally obtained, but specific data regarding
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Cited by (0)
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From the University Hospital Eppendorf, Department of Endoscopic Surgery, Hamburg, Germany.
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Reprint requests: K. F. Binmoeller, MD, University Hospital, Department of Endoscopic Surgery, Martinistrasse 52, 20246 Hamburg, Germany.
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