Original articleSerum samples from pancreatectomized patients contain trypsinogen immunoreactivity☆
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Cited by (10)
Trypsins and their role in carcinoma growth
2006, Experimental Cell ResearchCitation Excerpt :TAT-2 and trypsin-2 derived from pancreas have identical aminoterminal sequence, molecular weight, and immunoreactivity, but they differ in their activity against synthetic substrates, enzyme stability, and isoelectric point. These differences are probably due to post-translational modification that is different in pancreas and carcinomas [43,44,50,58]. The nucleotide sequence of TAT-2 and pancreatic trypsin-2 was identical except for one base substitution (G to A) [44].
Activation of type IV procollagenases by human tumor-associated trypsin- 2
1997, Journal of Biological ChemistryEndogenous proteases in tumoral progression
2017, Pathophysiological Aspects of ProteasesBiomarker development, from bench to bedside
2016, Critical Reviews in Clinical Laboratory SciencesHuman trypsinogens in the pancreas and in cancer
2010, Scandinavian Journal of Clinical and Laboratory Investigation
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Supported by grants from The Academy of Finland, the Sigrid Jusélius Foundation, The Finnish Cancer Institute, and The Finnish Social Insurance Institution.
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