Original articleEffects of long-term nutritional rehabilitation on body composition and clinical status in malnourished children and adolescents with cystic fibrosis*
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2018, Encyclopedia of Endocrine DiseasesLongitudinal trends in nutritional status and the relation between lung function and BMI in cystic fibrosis: A population-based cohort study
2013, American Journal of Clinical NutritionLeucine enhances aerosol performance of Naringin dry powder and its activity on cystic fibrosis airway epithelial cells
2011, International Journal of PharmaceuticsCitation Excerpt :This finding suggests that the technological improvement of immediate drug solubility and powder flowability, as well as the presence of the AA in N-Leu 1, may increase the drug uptake and improve the CF cell altered metabolism, reducing the toxicity observed for unprocessed rawN (Fig. 8a). In accordance, increased and altered basal protein catabolism has been reported in CF patients by many reports (Holt et al., 1985; Levy et al., 1985; Switzer et al., 2009). To study the anti-inflammatory effects of N in CF cells, we investigated the main molecular targets of NF-κB and MAPK/ERK pathways in CuFi1 in comparison to normal bronchial NuLi1 cells.
Use of the insulin pump in treat cystic fibrosis related diabetes
2009, Journal of Cystic FibrosisCitation Excerpt :We have also demonstrated an additional benefit on protein turnover using CSII. Multiple studies have demonstrated protein catabolism in CF [15,26,27]. In the post-absorptive state, the rate of appearance of leucine (leucine Ra) reflects the absolute protein breakdown rate.
Pulmonary Manifestations of Systemic Disorders
2008, Pediatric Respiratory Medicine
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Supported by a grant from the Canadian Cystic Fibrosis Foundation. Dr. Levy was supported by a fellowship from the Human Nutritin Research Council of Ontario for 1 year, and subsequently by a fellowship from the Canadian Cystic Fibrosis Foundation.