Bile ductular cholestasis: An ominous histopathologic sign related to sepsis and “cholangitis lenta”
References (20)
- et al.
Pathophysiology of cholestasis
Human Pathol.
(1970) - et al.
Torulopsis glabrata infections in patients with cancer. Increasing incidence and relationship to colonization
Am. J. Med.
(1976) - et al.
Cholestatic effects of Escherischia coli endotoxin on the isolated perfused rat liver
Gastroenterology
(1976) - et al.
Jaundice due to bacterial infection
Gastroenterology
(1979) - et al.
Intrahepatic cholestasis (“cholangiolitis”)
Gastroenterology
(1956) An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation
Gastroenterology
(1980)- et al.
Hepatic alterations in obstructive jaundice
Am. J. Clin. Pathol.
(1964) Cholestasis; extrahepatic obstruction and secondary biliary cirrhosis
Morphologic aspects of intrahepatic cholestasis
Intrahepatic cholestasis
Arch. Int. Med.
(1979)
Cited by (114)
Bile Duct Diseases
2023, MacSween's Pathology of the Liver, Eighth EditionTransplantation Pathology
2023, MacSween's Pathology of the Liver, Eighth EditionStructure, Function and Responses to Injury
2023, MacSween's Pathology of the Liver, Eighth EditionDevelopment and prognostic relevance of a histologic grading and staging system for alcohol-related liver disease
2021, Journal of HepatologyCitation Excerpt :Both canalicular and ductular cholestasis convey prognostic information in the whole study cohort, in the decompensated subgroup as well as in decompensated patients with hASH. This supports similar results of others29,31 and underscores the prognostic utility of morphological cholestasis as an integral factor of SALVE grading. Since most patients with ALD exhibit severe fibrosis or cirrhosis at first diagnosis, any stepwise staging method should allow sub-classification into prognostically meaningful categories.
Liver Pathology
2020, Pediatric Gastrointestinal and Liver Disease, Sixth EditionEvaluation of histologic changes in the livers of patients with early and late hepatic artery thrombosis
2019, Human PathologyCitation Excerpt :They can be seen in bile infarcts from other causes, and the latter in particular was seen in most cases in our small comparison group. We also observed ductular cholestasis in several cases; this is generally linked to sepsis [25,26], but it is not specific for that diagnosis, and indeed, most of our patients with this finding were not clinically septic. Frank bile duct necrosis with fibrosis and inflammation of the wall has also been described [3], but this was a rare occurrence in our series.
- *
Assistant Professor of Pathology, Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York.