Baillière's Clinical Gastroenterology
4 Mucosal allergy: role of mast cells and eosinophil granulocytes in the gut
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Cited by (58)
Effects of glycinin on IgE-mediated increase of mast cell numbers and histamine release in the small intestine
2008, Journal of Nutritional BiochemistryFood Allergy and Eosinophilic Gastrointestinal Disorders: Guiding Our Diagnosis and Treatment
2008, Current Problems in Pediatric and Adolescent Health CareCitation Excerpt :These generally target the eosinophilic inflammatory pathway. Anti-IL-5 or IL-5 gene deletion blocks induction of experimentally induced eosinophilic esophagitis in mice.90 Garrett and coworkers published a case study showing the effectiveness of anti-IL-5 in an adolescent male with hypereosinophilic syndrome and esophageal eosinophilia.105
General laboratory diagnostics of eosinophilic GI diseases
2008, Best Practice and Research: Clinical GastroenterologyGastrointestinal Eosinophilia
2007, Immunology and Allergy Clinics of North AmericaCitation Excerpt :A large percentage (approximately 10%) of patients suffering from EGID have an immediate family member with EGID [27]. Several lines of evidence support an allergic etiology, including the finding that approximately 75% of patients with EGID are atopic [21,28–34], that the severity of disease can sometimes be reversed by institution of an allergen-free diet [33–35], and the common finding of mast cell degranulation in tissue specimens [36,37]. Recent models of EGID support a potential allergic etiology for these disorders [38].
Adverse reactions to cows' milk
2007, Paediatrics and Child Health