Elsevier

Clinics in Liver Disease

Volume 7, Issue 1, February 2003, Pages 261-287
Clinics in Liver Disease

Appendix: The National Institutes of Health Consensus Development Conference: Management of Hepatitis C 2002

https://doi.org/10.1016/S1089-3261(02)00078-8Get rights and content

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Management of hepatitis C 2002: June 10–12, 2002

NIH Consensus Statements are prepared by a nonadvocate, nonfederal panel of experts, based on (1) presentations by investigators working in areas relevant to the consensus questions during a 2-day public session, (2) questions and statements from conference attendees during open discussion periods that are part of the public session, and (3) closed deliberations by the panel during the remainder of the second day and morning of the third. This statement is an independent report of the panel and

Summary

The incidence of newly acquired hepatitis C infection has diminished in the United States. This decline is largely because of a decrease in cases among IDUs for reasons that are unclear and, to a lesser extent, to testing of blood donors for HCV. The virus is transmitted by blood, and such transmission now occurs primarily through injection drug use, sex with an infected partner or multiple partners, and occupational exposure. Most infections become chronic, and therefore the prevalence of HCV

Recommendations

  • Educate the American public on the transmission of HCV in order to better identify affected individuals and to institute preventive measures.

  • Develop reliable, reproducible, and efficient culture systems for propagating HCV and expand basic research in the pathogenic mechanisms underlying hepatic fibrosis.

  • Promote the standardization and wide availability of diagnostic tests for HCV infection and its complications, leading to early diagnosis and the implementation of appropriate treatment

Consensus development panel

  • James L. Boyer, MD

  • Eugene B. Chang, MD

  • Deborah E. Collyar

  • Laurie D. DeLeve, MD, PhD

  • Judith Feinberg, MD

  • Thomas A. Judge, MD

  • Franco M. Muggia, MD

  • Charles L. Shapiro, MD

  • Stephen A. Spector, MD

  • Frederick J. Suchy, MD

  • Patricia L. Tomsko, MD, CMD

  • Barbara J. Turner, MD, MSEd

Speakers

  • Alfredo Alberti, MD

  • Miriam J. Alter, PhD

  • Bruce R. Bacon, MD

  • Gary L. Davis, MD

  • Adrian M. Di Bisceglie, MD

  • Jules L. Dienstag, MD

  • Brian R. Edlin, MD

  • Hashem B. El-Serag, MD, MPH

  • Michael W. Fried, MD

  • Kelly A. Gebo, MD, MPH

  • H. Franklin Herlong, MD

  • Jay H. Hoofnagle, MD

  • Maureen M. Jonas, MD

  • W. Ray Kim, MD, MSc, MBA

  • Karen L. Lindsay, MD

  • Anna S.F. Lok, MD

  • Patrick Marcellin, MD

  • John G. McHutchison, MD

  • Jean-Michel Pawlotsky, M, PhD

  • Marion G. Peters, MD, MBBS

  • Eve A. Roberts, MD, FRCPC

  • Leonard B. Seeff, MD

  • Mitchell L. Shiffman, MD

Planning committee

  • Leonard B. Seeff, MD

  • Miriam J. Alter, PhD

  • Luiz H. Barbosa, DVM

  • Eric B. Bass, MD, MPH

  • Jacqueline S. Besteman, JD, MA

  • John A. Bowersox

  • James L. Boyer, MD

  • Elsa A. Bray

  • John S. Cole III, PhD

  • Lawrence Deyton, MD, MSPH

  • Adrian M. Di Bisceglie, MD

  • Jules L. Dienstag, MD

  • Marguerite A. Evans, MS, RD

  • James Everhart, MD, MPH

  • Kelly A. Gebo, MD, MPH

  • Lt. Col. Roger Gibson, PhD, DVM, MPH

  • Jay H. Hoofnagle, MD

  • Leslye D. Johnson, PhD

  • Barnett S. Kramer, MD, MPH

  • Jake Liang, MD

  • Diane L. Lucas, PhD

  • Louis Marzella, MD, PhD

  • Karen Patrias, MLS

Conference sponsors

  • National Institute of Diabetes and Digestive and Kidney Diseases, Allen M. Spiegel, MD, Director

  • Office of Medical Applications of Research, Barnett S. Kramer, MD, MPH, Director

Conference cosponsors

  • National Institute of Child Health and Human Development, Duane Alexander, MD, Director

  • National Cancer Institute, Andrew C. von Eschenbach, MD

  • National Center for Complementary and Alternative Medicine, Stephen E. Straus, MD, Director

  • National Institute on Alcohol Abuse and Alcoholism, Raynard S. Kington, MD, PhD, Acting Director

  • National Institute on Drug Abuse, Glen R. Hanson, DDS, PhD, Acting Director

  • National Institute of Allergy and Infectious Diseases, Anthony S. Fauci, MD, Director

  • National

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