Severe attack of ulcerative colitis in children: retrospective clinical survey
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Cited by (22)
The Role of Noninvasive Surrogates of Inflammation in Monitoring Pediatric Inflammatory Bowel Diseases: The Old and the New
2023, Gastroenterology Clinics of North AmericaPredicting Outcomes in Pediatric Ulcerative Colitis for Management Optimization: Systematic Review and Consensus Statements From the Pediatric Inflammatory Bowel Disease–Ahead Program
2021, GastroenterologyCitation Excerpt :Age at diagnosis did not predict ASC in 2 retrospective studies of children with UC.27,44 One of these studies also found no association between ASC and disease extent.44 Statement 2.4.
Biological therapy in pediatric age
2020, Pharmacological ResearchCitation Excerpt :Of the total of 33 patients receiving IFX, 76 % were able to be discharged without colectomy and had a cumulative 1-year sustained response rate of 55 % (18/33). The advent of IFX together with calcineurin inhibitors has reduced the short-term colectomy rate from 40 %–70 % [17,22], to approximately 10 %–20 % in children [23,24] and the 1-year colectomy rate from 60 % to 18 %–22 % [25]. In a retrospective study conducted by Iwanczak et al. [26] 42 children (4–18 years) with moderate-severe UC were included.
Management of acute severe ulcerative colitis in children
2017, Seminars in Pediatric SurgeryCitation Excerpt :One prospective multicenter pediatric cohort study of ASUC where patients received the aforementioned dose reported a 71% response rate (95% CI: 63–78%).15 An analysis of a large prospective study of 128 children and 4 retrospective studies (143 patients in total) reported that failure rates to IV corticosteroid therapy in ASUC ranged between 9% and 47%.6,9,15,55–57 A subsequent meta-analysis of the published data from these 5 studies yielded a pooled estimate failure rate of 34% (95% CI: 27–41%) which is higher compared to adults.9
Colectomy in paediatric patients with ulcerative colitis
2011, Anales de PediatriaResponse to Corticosteroids in Severe Ulcerative Colitis: A Systematic Review of the Literature and a Meta-Regression
2007, Clinical Gastroenterology and HepatologyCitation Excerpt :Well-validated predictive indices could play an important role in the guideline development.50-62