Cancer Cell
Volume 36, Issue 3, 16 September 2019, Pages 319-336.e7
ArticleEpithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
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open access
Graphical Abstract
Keywords
colorectal cancer (CRC)
metastasis
molecular subtyping
serrated CRC
neutrophils
NOTCH1
TGF-β
consensus molecular subtype (CMS)
CRC intrinsic subtypes (CRIS)
tumor microenviroment (TME)
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