Original article—alimentary tractSerious Complications Within 30 Days of Screening and Surveillance Colonoscopy Are Uncommon
Section snippets
Setting and Participants
This prospective cohort study was performed within the Clinical Outcomes Research Initiative National Endoscopic Database (CORI), a nationwide data repository for gastrointestinal endoscopy procedures.20 Eighty-five centers and over 530 physicians participate in CORI. For this study, 18 CORI practices volunteered to participate, including 1 academic, 5 Veterans Administration (VA), and 12 private practice sites. VA sites were relatively overrepresented compared with CORI sites in general. The
Results
We recruited 21,375 patients, and were able to contact 18,271 at the 30 day time point. Seventy-six percent of subjects were enrolled from community-based practice settings. Characteristics of enrolled subjects were similar overall to eligible but not enrolled patients, except that a slightly higher percentage of nonenrolled subjects were from community-based practices (Table 1).
Discussion
The risk of serious complications within 30 days after screening and surveillance colonoscopy was low in our study, with an incidence of perforations of 0.19/1000 exams and gastrointestinal bleeding requiring hospitalization in 1.59/1000 exams. The overall incidence of serious, directly related complications was 2.01/1000 exams, and the incidence of all directly and potentially related events was 3.18/1000 exams (Table 3). Immediate procedure-related complications were uncommon (Table 2), and
Acknowledgments
The Centers for Disease Control and Prevention assisted in design, conduct, and analysis of this study. The funding sources had no role in the decision to submit the manuscript for publication.
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
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Conflict of interest The authors disclose no conflicts.
Funding This work was supported by the Centers for Disease Control and Prevention, Prevention Research Program, through the University of Washington Health Promotion Research Center, cooperative agreement numbers U48/CCU009654 and 1-U48-DP-000050, and by the National Institutes of Health grant (U01 DK057132) to Oregon Health and Sciences University.