Immunity
Volume 38, Issue 1, 24 January 2013, Pages 79-91
ArticleFate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
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Graphical Abstract
Highlights
► Most tissue macrophages are established before birth and are self-maintaining ► Ly6C+ monocytes are obligatory precursors of Ly6C− monocytes in steady state ► Ly6C+ monocytes negatively control lifespan of Ly6C− monocytes as Csf-1 sink
Cited by (0)
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These authors contributed equally to this work
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Present address: Division of Medicine, University College London, London WC1 6JJ, UK
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Present address: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA
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Present address: Laboratory of Immunoregulation and Mucosal Immunology, Department for Molecular Biomedical Research, VIB, Ghent, Belgium
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