ReviewSignalling pathways in alcohol-induced liver inflammation☆
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Keywords
Macrophages
Kupffer cells
TLRs
MAP kinases
Transcription factors
Abbreviations
ALD
alcoholic liver disease
Egr-1
early growth response factor-1
HSF
heat shock transcription factor
IRF
interferon-responsive factor
NFkB
nuclear factor kappa B
MAPK
mitogen activated protein kinase
MyD88
myeloid differentiation primary response gene (88)
STAT
signal transducers and activators of transcription
SOCS
suppressor of cytokine signalling
TLR
Toll-like receptor
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The underlying research reported in the study was funded by the NIH Institutes of Health, NIH AA017357 and AA015283 conference grant. The authors who have taken part in this study declared that they do not have anything to disclose regarding funding from industry or conflict of interest with respect to this manuscript.
Copyright © 2009 European Association for the Study of the Liver. Published by Elsevier Ireland Ltd.