Elsevier

La Presse Médicale

Volume 38, Issue 3, March 2009, Pages 499-500
La Presse Médicale

Clinical case
Severe acute ulcerated gastritis induced by salt

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Case report

A 20-year-old soldier was admitted to the emergency department, complaining of acute epigastric pain, vomiting, and afebrile watery diarrhea, which appeared 48 hours after ingestion of a small ladle of coarse salt mixed with a small amount of sparkling wine.

Results of the clinical examination, blood count, electrocardiography, chest X-radiography, and abdominal ultrasound were normal. On day 3 after ingestion, endoscopy of the upper digestive tract (figure 1) showed intense congestive antral

Discussion

Chronic salt ingestion induces gastric toxicity, which is known to be carcinogenic, and linked to gastric ulcer mortality [1], [2], [3], [4]. Acute gastric toxicity of salt ingestion has not previously been reported in humans to the best of our knowledge. Experimental studies in animals have shown that the gastric toxicity induced by acute salt ingestion is due to the decreased viability of gastric epithelial cells, which in turns induces proinflammatory cytokine production (e.g., TNF alpha and

Conflicts of interest

none

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