Abstract
Lechiguana is a disease of cattle characterized by large, hard, subcutaneous swellings that grow rapidly and result in death after 3–11 months in untreated animals. Cattle treated with antibiotics recover. The disease has been reported from five states in south and southeastern Brazil. Histologically, the lesion consists of focal proliferation of fibrous tissue infiltrated by plasma cells, eosinophils, lymphocytes and sometimes neutrophils. The primary lesion is an eosinophilic lymphangitis, which results in eosinophilic abscesses, with occasional rosettes containing bacteria in their centres. Much experimental and epidemiological evidence, reviewed in this article, supports the suggestion that lechiguana is caused by an association of Pasteurella granulomatis (syn: Mannheimia granulomatis) and Dermatobia hominis.
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REFERENCES
Andrade, G.B., 1999. Estudo histoquímico, morfométrico e molecular do colágeno na paniculite fibrogranu-lomatosa focal dos bovinos (lechiguana), (PhD thesis, University of São Paulo, Brazil)
Andrade, G.B., Riet-Correa, F., Montes, G.S., Battlenhner, C.N. and Saldiva, P.H.N., 1997. Dating of fibrotic lesions by Picrosirius-polarization method. An application using the lesion of lechiguana (bovine focal proliferative fibromatous-panniculitis). European Journal of Histochemistry, 41, 203-209
Angen, O., Mutters, R., Caugant, D.A., Olsen, J.E. and Bisgaard, M., 1999. Taxonomic relationships of the (Pasteurella) haemolytica complex as evaluated by DNA–DNA hybridizations and 16s rRNA sequencing with proposal of Mannheimia haemolytica gen. nov., comb. nov., Mannheimia granulomatis comb. nov.,Mannheimia glucosida sp. nov.,Mannheimia ruminalis sp. nov. and Mannheimia varigena sp. nov. International Journal of Systemic Bacteriology, 1, 67-86
Bauer, W., Kirby, W.M.N., Sherris, J.C. and Turck, M., 1966. Antibiotic susceptibility testing by standardized single disk method. American Journal of Clinical Pathology, 45, 493-496
Birgel, E.H. Jr, Ollhoff, R.D., Benesi, F.J., Viana, R.B., Schalch, U.M., Pacheco, J.C.G., Florio, W.A.B., Ramos, M.C.C. and Birgel, E.H., 1999. Ocorrência de Lechiguana (paniculite fibrogranulomatosa proliferativa) em bovino criado no Estado de São Paulo. Arquivos do Instituto Biológico, 66(supplement), 130
Cardoso, C.M., 1998. Lechiguana: experimental histologic lesions and study of new cases, (MS thesis, University of Pelotas, Brazil)
Ladeira, S.L., Riet-Correa, F., Pereira, D.B. and Carter, G.R., 1996. Role of Pasteurella granulomatis and Dermatobia hominis in the etiology of lechiguana in cattle. Annals of the NewYork Academy of Sciences, 791, 359-368
Martins, L.A., 1998. Modulation of the immune response in experimental animals inoculated with Pasteurella granulomatis, (MS thesis, University of the State of São Paulo, UNESP, Brazil)
Montes, G.L. and Junqueira, L.C.U., 1991. The use of Picrosirius-polarization method for the study of the biopathology of the collagen. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, 86, 1-11
Pereira, D.B., 1996. Lechiguana: Pathogenic aspects, Pasteurella granulomatis carriers and new cases of the disease in cattle, (MS thesis, University of Pelotas, Brazil)
Ribeiro, G.A., Carter, G.R., Frederiksen, W. and Riet-Correa, F., 1989. Pasteurella haemolytica-like bacterium from a progressive granuloma of cattle in Brazil. Journal of Clinical Microbiology, 27, 1401-1402
Ribeiro, G.A., 1998. Míiases. In: F. Riet-Correa, A.L. Schild and M.C Mendez (eds), Doenças de ruminantes e eqüinos, (Gráfica Universitária, Pelotas, RS), 374-382
Riet-Correa, F., Almeida, S.M., Méndez, M.C., Schild, A.L. and Ribeiro, G.A., 1989. Reprodução experimental de um granuloma progressivo em bovinos conhecido como ``Lechiguana''. A Hora Veterinária, 47, 25-28
Riet-Correa, F., Méndez, M.C., Schild, A.L., Ribeiro, G.A. and Almeida, S.M., 1992. Bovine focal proliferative fibrogranulomatous panniculitis (lechiguana) associated with Pasteurella granulomatous. Veterinary Pathology, 29, 93-103
Varaschin, M.S. and Silva, A.M., 1998. Paniculite fibrogranulomatosa focal em bovino de Minas Gerais. Ciêcia Rural, 28, 151-153
Veit, H.P., Carter, G.R., Riet-Correa, F. and Brown, S.S., 1996. The use of polymerase chain reaction to identify Pasteurella granulomatis from cattle. Annals of the New York Academy of Sciences, 791, 350-358
Veit, H.P., Wise, D.J., Carter, G.R. and Chengappa, M.M., 1998. Toxin production by Pasteurella granulomatis. Annals of the NewYork Academy of Sciences, 849, 479-484
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Riet-Correa, F., Ladeira, S., Andrade, G. et al. Lechiguana (Focal Proliferative Fibrogranulomatous Panniculitis) in Cattle. Vet Res Commun 24, 557–572 (2000). https://doi.org/10.1023/A:1006444019819
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DOI: https://doi.org/10.1023/A:1006444019819