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Systemic Endotoxemia during Chronic Viral Hepatitis

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Abstract

Incidence and severity of systemic endotoxemia in patients with chronic viral hepatitis B and C were studied using the limulus test. Healthy subjects and patients with acute viral hepatitis B and C comprised reference groups. The incidence of "physiological" systemic endotoxemia in healthy subjects was 31.3%, while in chronic hepatitis systemic endotoxemia was found in 69-84% patients and it was more severe in this case. A significant correlation was revealed between systemic endotoxemia with virus replication and the degree of basic clinical and laboratory signs in patients with chronic viral hepatitis B.

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Correspondence to A. S. Sozinov.

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Sozinov, A.S. Systemic Endotoxemia during Chronic Viral Hepatitis. Bulletin of Experimental Biology and Medicine 133, 153–155 (2002). https://doi.org/10.1023/A:1015546821875

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  • DOI: https://doi.org/10.1023/A:1015546821875

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