Clinical ResearchClinical and pathophysiological characteristics of acute-onset functional dyspepsia☆
Section snippets
Study subjects
A total of 400 consecutive patients with functional dyspepsia (275 female and 125 male patients; age range, 16–84 years; mean age, 42.8 ± 0.8 years) participated in this study. Twenty healthy volunteers (15 men and 5 women; age range, 19–34 years; mean age, 24 ± 1 years) were studied as controls. None of the healthy subjects reported symptoms or a history of gastrointestinal disease, drug allergies, or that they were taking any medication.
Patients presented to the general gastroenterology
Characteristics of patients with functional dyspepsia
Table 1 summarizes the grading of dyspeptic symptoms in the patient group.Empty Cell 0 (Absent) 1 (Mild) 2 (Relevant) 3 (Severe) Postprandial fullness 63 (16) 37 (9) 148 (37) 152 (38) Bloating 75 (19) 35 (9) 172 (40) 128 (32) Epigastric pain 146 (37) 42 (10) 97 (24) 115 (29) Early satiety 163 (41) 42 (10) 104 (26) 91 (23) Nausea 152 (38) 52 (13) 115 (29) 80 (20) Vomiting 282 (70) 18 (5) 41 (10) 59 (15) Belching 169 (42) 54 (14)
Discussion
Functional dyspepsia is one of the most frequently encountered disorders of the gastrointestinal tract, accounting for up to 5% of consultations with general practitioners.21 Although recent studies have improved our understanding of the underlying pathophysiologic disturbances and their association with specific symptom patterns, the pathogenesis of functional dyspepsia has remained obscure. In the present study, using a questionnaire, 25% of patients with functional dyspepsia reported an
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Functional dyspepsia
2023, Handbook of Gastrointestinal Motility and Disorders of Gut-Brain Interactions, Second EditionPost-infection Irritable Bowel Syndrome
2021, Gastroenterology Clinics of North AmericaCitation Excerpt :Functional dyspepsia (FD) is another common functional GI disorder that causes epigastric pain, postprandial fullness, and early satiety. Its development after infectious gastroenteritis has been reported,40 with a prevalence of ∼9% and a relative risk (RR) of 2.5 in a systematic review of 19 studies.41 An overlap between PI-IBS and PI-FD can exist, as shown after giardiasis, where 26% developed PI-FD, 85% of whom also met criteria for PI-IBS.42
Sex- and Gender-Related Differences in Common Functional Gastroenterologic Disorders
2021, Mayo Clinic ProceedingsCitation Excerpt :The relationship between sex and the risk of postinfectious FD is unclear. The sex distribution of patients with postinfectious and unspecified-onset FD is comparable91 or different.92 A meta-analysis of risk factors for postinfectious FD did not study sex.93
Gender-Related Differences in Gastroparesis
2020, American Journal of the Medical SciencesIdiopathic gastroparesis
2020, Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment
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Address requests for reprints to: Jan Tack, M.D., Ph.D., Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium. e-mail: [email protected]; fax: (32) 16-34-44-19.