Original ArticlesEating behavior in Prader-Willi syndrome, normal weight, and obese control groups☆,☆☆
Section snippets
Subjects and methods
Subjects with PWS (7 boys, 2 girls), 20 normal weight subjects (11 boys, 9 girls), and 20 subjects in an obese group (8 boys, 12 girls) participated in this study. The groups were age-matched as far as possible, and all subjects were between the ages of 5 and 18 years (Table I).Empty Cell PWS (n = 9) Normal weight (n = 20) Obese (n = 20) Sex 7 boys/2 girls 11 boys/9 girls 8 boys/12 girls Age (y) 9.9 ± 4.3 (5.0-17.5) 11.8 ± 3.3
Results
The food intake, the duration of consumption, the eating rate, and the rate of deceleration calculated as median and range for all groups are shown in Table II.Empty Cell PWS (n = 9) Normal weight (n = 20) Obese (n = 20) Kruskal-Wallis test Intake (g) 267 (162-532) 270 (92-497) 314 (125-535) NS Time of consumption (min) 21.4 (5.8-43.9) 9.9 (4.0-28.7) 7.7 (3.8-19.0) P =.04 Eating rate (initial, g/min) 19 (3-46) 40 (12-93) 47 (17-79) P <.01 Eating
Discussion
A decelerating eating curve, the most common type of eating pattern,8, 9, 10, 11 has also been called a biologic satiation curve,12 that is, an eating curve with a high initial eating rate when the test subject is hungry and the drive to eat is high, followed by a gradual decrease in eating rate until satiety occurs and the meal is terminated. Satiety is the state that occurs after a meal and affects the time interval to the next meal; satiation is the process that brings eating to an end. If a
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Cited by (0)
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Supported by grants from Resource Centre for Eating Disorders, the Foundations of Vera Ekström, Eugenia and Sunnerdahl, the Society for Child Care, the Karolinska Institute, Swedish Medical Research Council grant number 9941 and the Swedish National Association for Disabled Children and Young People.
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Reprint requests: Ann Christin Lindgren, MD, PhD, Pediatric Endocrinology Unit, Astrid Lindgren’s Children’s Hospital, Karolinska Hospital, S-171 76 Stockholm, Sweden.