European Journal of Gastroenterology & Hepatology

Accession Number<strong>00042737-200102000-00016</strong>.
AuthorCampbell, Simon; Ghosh, Subrata
InstitutionGastrointestinal Unit, Western General Hospital, Edinburgh, UK
TitleInfliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection.[Report]
SourceEuropean Journal of Gastroenterology & Hepatology. 13(2):191-192, February 2001.
AbstractTreatment of Crohn's disease with infliximab is an important drug therapy for patients with refractory and fistulating disease. There are concerns over its use in a proportion of Crohn's patients with concurrent hepatitis C infection, since there are theoretical risks of accelerated hepatic decompensation due to the immunomodulatory impact of infliximab. We report a patient with both Crohn's disease and ongoing active hepatitis C infection who underwent infliximab therapy, with no worsening of his liver function or PCR status.

(C) 2001 Lippincott Williams & Wilkins, Inc.