Accession Number | <strong>00042737-200102000-00016</strong>. |
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Author | Campbell, Simon; Ghosh, Subrata |
Institution | Gastrointestinal Unit, Western General Hospital, Edinburgh, UK |
Title | |
Source | European Journal of Gastroenterology & Hepatology. 13(2):191-192, February 2001. |
Abstract | Treatment of Crohn's disease with infliximab is an important drug therapy for patients with refractory and fistulating disease. There are concerns over its use in a proportion of Crohn's patients with concurrent hepatitis C infection, since there are theoretical risks of accelerated hepatic decompensation due to the immunomodulatory impact of infliximab. We report a patient with both Crohn's disease and ongoing active hepatitis C infection who underwent infliximab therapy, with no worsening of his liver function or PCR status. (C) 2001 Lippincott Williams & Wilkins, Inc. |