Pancreatic Intraepithelial Neoplasia Revisited and Updated
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Cited by (94)
Pancreatic intraepithelial neoplasia detection and duct pathology grading using FT-IR imaging and machine learning
2024, Spectrochimica Acta - Part A: Molecular and Biomolecular SpectroscopyCarcinoma of the Pancreas
2019, Abeloff’s Clinical OncologyBiology, pathophysiology, and epidemiology of pancreatic cancer
2019, Theranostic Approach for Pancreatic CancerPancreatic cancer chemo-resistance is driven by tumor phenotype rather than tumor genotype
2018, HeliyonCitation Excerpt :Oncogenic KRAS activates the MAP (Mitogen Activate Protein) kinase and the PI3 (Phosphoinositide 3) kinase pathways, leading to an increased proliferation. KRAS mutation is considered as an early event during pancreatic carcinogenesis occurring in 35% of low grade PanINs and reaching 75% in high grade PanINs [10]. This mutation facilitates the progression from low grade to high grade PanINs and is sufficient to initiate the PanIN lesions.
Diagnostic Pathology: Hepatobiliary and Pancreas
2017, Diagnostic Pathology: Hepatobiliary and Pancreas
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PD Dr. Bence Sipos Department of Pathology, University of Kiel Michaelisstrasse 11 DE-24105 Kiel (Germany) Tel. +49 431 597 3402, Fax +49 431 597 3462
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