Mediating mismatch repair

Nat Genet. 2000 Jan;24(1):6-8. doi: 10.1038/71698.

Abstract

The DNA repair picture in humans becomes more complete with the identification of MLH3, a homologue of MutL and a heterodimeric partner of MLH1.

Publication types

  • News

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Animals
  • Base Pair Mismatch*
  • Base Sequence
  • Carrier Proteins
  • Colorectal Neoplasms, Hereditary Nonpolyposis / genetics
  • DNA / genetics
  • DNA Repair / genetics*
  • Dimerization
  • Humans
  • MutL Protein Homolog 1
  • Mutation
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism
  • Nuclear Proteins

Substances

  • Adaptor Proteins, Signal Transducing
  • Carrier Proteins
  • MLH1 protein, human
  • Neoplasm Proteins
  • Nuclear Proteins
  • DNA
  • MutL Protein Homolog 1