Ornidazole-induced autoimmune hepatitis

Eur J Gastroenterol Hepatol. 2001 Jun;13(6):737-9. doi: 10.1097/00042737-200106000-00022.

Abstract

Ornidazole is a commonly prescribed antiparasitic drug for parasitic infestations, including amoebiasis, giardiasis and Trichomonas vaginalis. Several cases of antibiotic-induced autoimmune hepatitis (AIH) or AIH-like syndrome have been reported recently. In this report, we describe a 35-year-old woman with two relapses of AIH induced by ornidazole prescribed for diarrhoea and vaginal infection.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Adult
  • Biopsy, Needle
  • Diarrhea / diagnosis
  • Diarrhea / drug therapy*
  • Female
  • Follow-Up Studies
  • Hepatitis, Autoimmune / drug therapy
  • Hepatitis, Autoimmune / etiology*
  • Hepatitis, Autoimmune / pathology*
  • Humans
  • Liver Function Tests
  • Ornidazole / administration & dosage
  • Ornidazole / adverse effects*
  • Risk Assessment
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Ornidazole