MGMT: its role in cancer aetiology and cancer therapeutics

Nat Rev Cancer. 2004 Apr;4(4):296-307. doi: 10.1038/nrc1319.

Author

Stanton L Gerson¹

Affiliation

¹ Case Comprehensive Cancer Center, University Hospitals of Cleveland and Case Western Reserve University, 10900 Euclid Ave, Cleveland, Ohio 44106, USA. slg5@case.edu

PMID: 15057289
DOI: 10.1038/nrc1319

No abstract available

Publication types

Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Cell Transformation, Neoplastic / genetics
DNA Methylation
DNA Repair / physiology*
Drug Resistance, Neoplasm / genetics
Genetic Therapy
Humans
Neoplasms / drug therapy
Neoplasms / enzymology*
Neoplasms / etiology
O(6)-Methylguanine-DNA Methyltransferase / genetics
O(6)-Methylguanine-DNA Methyltransferase / physiology*
Promoter Regions, Genetic

Substances

O(6)-Methylguanine-DNA Methyltransferase