Abstract
Robert L. Coffman recounts how his work on immunoglobulin E regulation along with data from Tim Mosmann on the functional heterogeneity of T cell clones led to the T helper type 1-T helper type 2 hypothesis.
Publication types
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Biography
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Historical Article
MeSH terms
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Allergy and Immunology / history*
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Animals
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History, 20th Century
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History, 21st Century
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Humans
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Models, Immunological
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Th1 Cells / immunology*
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Th2 Cells / immunology*