Enteroscopic diagnosis of small bowel ulceration in patients receiving non-steroidal anti-inflammatory drugs

Lancet. 1991 Mar 2;337(8740):520. doi: 10.1016/0140-6736(91)91300-j.

Abstract

15 patients with rheumatoid arthritis who were receiving non-steroidal anti-inflammatory drugs (NSAIDs) and who had chronic occult gastrointestinal bleeding underwent extended small bowel examination with a Sonde enteroscope. 7 patients (47%) were found to have jejunal or ileal ulceration. Small bowel enteroscopy may be a valuable technique for the investigation of undiagnosed gastrointestinal bleeding.

MeSH terms

  • Adult
  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Evaluation Studies as Topic
  • Female
  • Gastroenterology / instrumentation
  • Gastroenterology / methods*
  • Humans
  • Ileal Diseases / chemically induced
  • Ileal Diseases / diagnosis*
  • Jejunal Diseases / chemically induced
  • Jejunal Diseases / diagnosis*
  • Male
  • Middle Aged
  • Ulcer / chemically induced
  • Ulcer / diagnosis

Substances

  • Anti-Inflammatory Agents, Non-Steroidal