Prophet, a web-based tool for class prediction using microarray data

Bioinformatics. 2007 Feb 1;23(3):390-1. doi: 10.1093/bioinformatics/btl602. Epub 2006 Nov 30.

Abstract

Sample classification and class prediction is the aim of many gene expression studies. We present a web-based application, Prophet, which builds prediction rules and allows using them for further sample classification. Prophet automatically chooses the best classifier, along with the optimal selection of genes, using a strategy that renders unbiased cross-validated errors. Prophet is linked to different microarray data analysis modules, and includes a unique feature: the possibility of performing the functional interpretation of the molecular signature found.

Availability: Prophet can be found at the URL http://prophet.bioinfo.cipf.es/ or within the GEPAS package at http://www.gepas.org/

Supplementary information: http://gepas.bioinfo.cipf.es/tutorial/prophet.html.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Cluster Analysis*
  • Gene Expression Profiling / methods*
  • Internet*
  • Multigene Family / physiology*
  • Oligonucleotide Array Sequence Analysis / methods*
  • Pattern Recognition, Automated / methods
  • Proteins / classification
  • Proteins / metabolism*
  • Signal Transduction / physiology
  • Software*

Substances

  • Proteins