Omeprazole inhibits IL-4 and IL-13 signaling signal transducer and activator of transcription 6 activation and reduces lung inflammation in murine asthma

J Allergy Clin Immunol. 2009 Sep;124(3):607-10, 610.e1. doi: 10.1016/j.jaci.2009.06.023. Epub 2009 Aug 8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 2-Pyridinylmethylsulfinylbenzimidazoles / administration & dosage
  • Animals
  • Asthma / drug therapy*
  • Asthma / immunology
  • Cell Line, Tumor
  • Disease Models, Animal
  • Interleukin-13 / antagonists & inhibitors
  • Interleukin-4 / antagonists & inhibitors*
  • Mice
  • Omeprazole / administration & dosage*
  • Pantoprazole
  • Phosphorylation / drug effects
  • Pneumonia / drug therapy*
  • Pneumonia / immunology
  • Proton Pump Inhibitors / administration & dosage*
  • STAT6 Transcription Factor / antagonists & inhibitors*
  • Signal Transduction / drug effects
  • Signal Transduction / immunology

Substances

  • 2-Pyridinylmethylsulfinylbenzimidazoles
  • Interleukin-13
  • Proton Pump Inhibitors
  • STAT6 Transcription Factor
  • Stat6 protein, mouse
  • Interleukin-4
  • Pantoprazole
  • Omeprazole