Adherence of gastroenterologists to European Crohn's and Colitis Organisation consensus on ulcerative colitis: a real-life survey in Spain

J Crohns Colitis. 2010 Nov;4(5):567-74. doi: 10.1016/j.crohns.2010.06.001. Epub 2010 Jul 6.

Abstract

Background & aims: A European consensus on the management of ulcerative colitis (UC) was recently published; however, there is no adequate evidence about adherence to such guidelines among gastroenterologists. This knowledge would allow the local evaluation of the situation and the adoption of actions to reduce the existent clinical variability.

Methods: A cross-sectional survey was conducted in Spain to assess the adherence to the European Crohn's and Colitis Organisation (ECCO) guidelines on mild to moderate UC. We surveyed 700 gastroenterologists, and finally a total of 530 gastroenterologists specialised in inflammatory bowel disease (GSIBDs) and general gastroenterologists (GGs), responded to the survey (76%).

Results: Agreement with the guidelines was high; discrepancies included that only 25% of the GGs used the combination of oral and topical 5-aminosalycilic acid (5-ASA) for treating extensive UC vs 45% of the GISBDs. In addition, topical rectal steroids were considered as effective as topical mesalazine by 48% of the GGs vs 31% of the GSIBDs, indefinite treatment with 5-ASA was prescribed by only 26% of the GGs vs 41% of the GSIBDs, and the once daily dosing of 5-ASA was generally used by 46% of the GGs vs 51% of the GSIBDs.

Conclusions: The questionnaire showed a high degree of agreement between GGs and GSIBDs. Nevertheless, the GSIBD group showed closer agreement with the ECCO guidelines. Furthermore, some shortcomings were found in the GG group, in which increased maintenance treatment with 5-ASA, the use of a single daily dose of 5-ASA, and the use of combined oral and topical treatment for distal colitis should be advised.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Colitis, Ulcerative / diagnosis*
  • Colitis, Ulcerative / drug therapy*
  • Cross-Sectional Studies
  • Europe
  • Gastroenterology / standards*
  • Guideline Adherence*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Mercaptopurine / therapeutic use
  • Mesalamine / therapeutic use
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians'*
  • Spain
  • Surveys and Questionnaires

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Immunosuppressive Agents
  • Mesalamine
  • Mercaptopurine