Abstract
A new optogenetics study finds that stimulation of pro-opiomelanocortin (POMC) and agouti-related peptide (AGRP) neurons acutely regulates feeding behavior. AGRP-induced hyperphagia is independent of melanocortin signaling.
MeSH terms
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Agouti-Related Protein / metabolism*
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Animals
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Channelrhodopsins
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Eating
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Feeding Behavior / physiology*
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Hypothalamus / physiology*
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Light*
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Melanocortins / metabolism
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Mice
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Neurons / metabolism
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Pro-Opiomelanocortin / metabolism*
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Signal Transduction / physiology
Substances
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Agouti-Related Protein
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Channelrhodopsins
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Melanocortins
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Pro-Opiomelanocortin